Sr. Technical Program Manager, Infrastructure Rationalization

The Role:

Moderna is seeking a Senior Technical Program Manager (TPM) to drive project and program management of infrastructure (cloud and on‑prem) rationalization and AI‑readiness initiatives at Moderna globally. We’re looking for someone with a high level of integrity and personal accountability, strong interpersonal skills, and infrastructure technology domain expertise.

• Program Management – take a structured, data‑driven, and risk‑based approach to program scoping, execution, and reporting
• Kick off and successfully manage multiple, simultaneous, complex, high visibility work streams with full ownership, effective collaboration, and good process
• Build processes, templates, and structure, or leverage existing ones as appropriate
• Manage vendors, schedule, scope, and cost
• Measure program success (or lack thereof) and risks using data and facts
• Provide balanced risk remediation strategies and recommendations and drive risk mitigation
• Develop and maintain close stakeholder relationships and build influence to drive the appropriate outcomes across Moderna
• Provide clear, accurate, consistent, and timely communications
• Advance good infrastructure and security practices and culture
• Partner Collaboration work with Cloud Engineering, Systems Engineering, and AI Engineering, as well as Network Engineering, Identity and Access Management, Builder Tools & Platforms, IT, Cybersecurity, software engineering, and business stakeholders to manage and drive improvement projects in a structured and predictable manner
• Manage multiple initiatives:
• Cloud modernization
• Rationalize infrastructure platforms, tooling, and service models that underpin AI workloads
• Identify and eliminate redundant, unsupported, or non‑scalable infrastructure patterns that impede AI adoption
• Enable standardized, secure, and supportable “AI‑ready” infrastructure foundations that accelerate time‑to‑value while managing cost and risk
• Ensure infrastructure rationalization aligns with AI governance, data protection, and compliance requirements
• Define and track KPIs related to platform consolidation, cost optimization, risk reduction, and AI enablement readiness
• Lead and drive infrastructure service management improvements and process optimization initiatives, including infrastructure patch and vulnerability management
• Actively contribute to creating a more inclusive culture and environment at Moderna; endorse, create, and maintain antiracist policies and processes

• 8+ years of program management experience, preferably in infrastructure engineering
• Demonstrated technical depth, problem‑solving capabilities, and stakeholder and vendor management skills
• Technical background in infrastructure engineering, with a strong understanding of ITSM
• Experience in running programs within a cross‑functional, global team of mixed engineering, architecture, and operations
• Ability to successfully scope and drive complex and multi‑workstream programs in a structured, risk‑considerate, data‑driven fashion
• Strong listener with the ability to deeply understand, ask the right questions, and proactively pursue constructive feedback
• Proven ability to operate in highly matrixed environments and influence without direct authority

• Strong understanding of cloud platforms (AWS, Azure)
• Familiarity with infrastructure concepts: compute, storage, networking, containers, Kubernetes
• Working knowledge of AI/ML infrastructure needs (GPUs, distributed training, data pipelines, MLOps)
• Influential, inclusive, and trusted partner compassionate to the needs and situations of all your stakeholders
• Deep familiarity with ITSM frameworks (e.g., ITIL)
• Experience driving structured, process‑driven infrastructure transformation initiatives
• Knowledge of security and compliance standards relevant to infrastructure operations
• Embrace a culture of continuous service improvement and service excellence
• A desire to make an impact as part of a high‑growth, transformational company
• Experience with GxP environments and regulatory requirements

At Moderna, we believe that when you feel your…