Temporary Scientist II
Listed on 2026-09-22
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Research/Development
Pharmaceutical Science/ Research, Research Scientist, Biotech Research
We are seeking a Scientist, Bioanalytical Sciences to support drug discovery and DMPK research activities with a focus on LC-MS/MS bioanalysis of small molecules, pharmacokinetic (PK) analysis, and preclinical study support. This role will contribute to bioanalytical data generation, PK reporting, formulation testing, and ADME-related activities to advance research programs.
The ideal candidate will possess strong hands‑on LC-MS/MS experience, a solid understanding of pharmacokinetics, and experience working with biological matrices in a research environment.
Key ResponsibilitiesPosition Overview
We are seeking a Scientist, Bioanalytical Sciences to support drug discovery and DMPK research activities with a focus on LC-MS/MS bioanalysis of small molecules, pharmacokinetic (PK) analysis, and preclinical study support. This role will contribute to bioanalytical data generation, PK reporting, formulation testing, and ADME-related activities to advance research programs.
The ideal candidate will possess strong hands‑on LC-MS/MS experience, a solid understanding of pharmacokinetics, and experience working with biological matrices in a research environment.
- Perform LC-MS/MS bioanalysis of small molecules in biological matrices including plasma, blood, serum, tissue, and related preclinical samples.
- Conduct bioanalytical testing to support pharmacokinetic (PK), toxicokinetic (TK), pharmacodynamic (PD), efficacy, and drug discovery studies.
- Prepare and process biological samples using established extraction and bioanalytical methods.
- Operate, maintain, and troubleshoot LC-MS/MS instrumentation and associated laboratory equipment.
- Perform PK data analysis and contribute to PK report generation and study interpretation.
- Support DMPK activities through data generation, analysis, reporting, and database management.
- Assist with formulation development, formulation testing, and in vitro stability assessments.
- Support ADME studies, including metabolic stability, hepatocyte, microsomal, plasma stability, and protein binding evaluations.
- Coordinate activities with external research partners and contribute to study execution and data review.
- Maintain accurate laboratory documentation, analyze experimental results, and communicate findings to project teams.
- Bachelor's degree in Chemistry, Pharmaceutical Sciences, Biochemistry, Biology, Pharmacology, or a related scientific discipline with 2+ years of relevant experience; or a Master's degree with 1+ year of relevant experience.
- Hands‑on experience performing LC-MS/MS bioanalysis of small molecules in biological matrices.
- Experience supporting PK data analysis and interpretation.
- Knowledge of bioanalytical sample preparation, extraction techniques, and laboratory workflows.
- Strong data analysis, documentation, and organizational skills.
- Proficiency with Excel and standard data analysis tools.
- Excellent communication and collaboration skills.
- Experience using Phoenix Win Nonlin or similar pharmacokinetic analysis software.
- Experience supporting DMPK and ADME studies.
- Experience with preclinical formulation development or in vitro formulation testing.
- Familiarity with HRMS, QTOF, or other advanced mass spectrometry platforms.
- Experience working with CROs or external laboratory partners.
- Experience in pharmaceutical, biotechnology, CRO, or drug discovery research environments.
- Strong analytical and problem‑solving skills.
- Hands‑on laboratory expertise and attention to detail.
- Ability to troubleshoot instrumentation and experimental challenges.
- Effective project prioritization and time management.
- Strong written and verbal communication skills.
- Ability to work independently and collaboratively in a fast‑paced research…
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