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Temporary Scientist II

Job in Alameda, Alameda County, California, 94501, USA
Listing for: Advanced Clinical
Seasonal/Temporary position
Listed on 2026-09-22
Job specializations:
  • Research/Development
    Pharmaceutical Science/ Research, Research Scientist, Biotech Research
Salary/Wage Range or Industry Benchmark: 85000 - 120000 USD Yearly USD 85000.00 120000.00 YEAR
Job Description & How to Apply Below

We are seeking a Scientist, Bioanalytical Sciences to support drug discovery and DMPK research activities with a focus on LC-MS/MS bioanalysis of small molecules, pharmacokinetic (PK) analysis, and preclinical study support. This role will contribute to bioanalytical data generation, PK reporting, formulation testing, and ADME-related activities to advance research programs.

The ideal candidate will possess strong hands‑on LC-MS/MS experience, a solid understanding of pharmacokinetics, and experience working with biological matrices in a research environment.

Key Responsibilities

Position Overview

We are seeking a Scientist, Bioanalytical Sciences to support drug discovery and DMPK research activities with a focus on LC-MS/MS bioanalysis of small molecules, pharmacokinetic (PK) analysis, and preclinical study support. This role will contribute to bioanalytical data generation, PK reporting, formulation testing, and ADME-related activities to advance research programs.

The ideal candidate will possess strong hands‑on LC-MS/MS experience, a solid understanding of pharmacokinetics, and experience working with biological matrices in a research environment.

  • Perform LC-MS/MS bioanalysis of small molecules in biological matrices including plasma, blood, serum, tissue, and related preclinical samples.
  • Conduct bioanalytical testing to support pharmacokinetic (PK), toxicokinetic (TK), pharmacodynamic (PD), efficacy, and drug discovery studies.
  • Prepare and process biological samples using established extraction and bioanalytical methods.
  • Operate, maintain, and troubleshoot LC-MS/MS instrumentation and associated laboratory equipment.
  • Perform PK data analysis and contribute to PK report generation and study interpretation.
  • Support DMPK activities through data generation, analysis, reporting, and database management.
  • Assist with formulation development, formulation testing, and in vitro stability assessments.
  • Support ADME studies, including metabolic stability, hepatocyte, microsomal, plasma stability, and protein binding evaluations.
  • Coordinate activities with external research partners and contribute to study execution and data review.
  • Maintain accurate laboratory documentation, analyze experimental results, and communicate findings to project teams.
Required Qualifications
  • Bachelor's degree in Chemistry, Pharmaceutical Sciences, Biochemistry, Biology, Pharmacology, or a related scientific discipline with 2+ years of relevant experience; or a Master's degree with 1+ year of relevant experience.
  • Hands‑on experience performing LC-MS/MS bioanalysis of small molecules in biological matrices.
  • Experience supporting PK data analysis and interpretation.
  • Knowledge of bioanalytical sample preparation, extraction techniques, and laboratory workflows.
  • Strong data analysis, documentation, and organizational skills.
  • Proficiency with Excel and standard data analysis tools.
  • Excellent communication and collaboration skills.
Preferred Qualifications
  • Experience using Phoenix Win Nonlin or similar pharmacokinetic analysis software.
  • Experience supporting DMPK and ADME studies.
  • Experience with preclinical formulation development or in vitro formulation testing.
  • Familiarity with HRMS, QTOF, or other advanced mass spectrometry platforms.
  • Experience working with CROs or external laboratory partners.
  • Experience in pharmaceutical, biotechnology, CRO, or drug discovery research environments.
Key Competencies
  • Strong analytical and problem‑solving skills.
  • Hands‑on laboratory expertise and attention to detail.
  • Ability to troubleshoot instrumentation and experimental challenges.
  • Effective project prioritization and time management.
  • Strong written and verbal communication skills.
  • Ability to work independently and collaboratively in a fast‑paced research…
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