Analytical Chemist​/Scientist

Pow.

Bio Analytical Chemist/Scientist

Alameda, CA

Full time

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www.pow.bio

Pow.

Bio is building the next generation of industrial biomanufacturing platforms and is a pioneer in AI-enabled continuous fermentation technology. We enable high-performance, continuous and decoupled fermentation processes that dramatically improve productivity, robustness, and scalability across food, nutrition, and industrial biotechnology applications.

Our work spans organism-agnostic fermentation, advanced process automation, and tightly integrated upstream and downstream operations—bridging bench-scale innovation with real-world manufacturing. Pow.

Bio is headquartered in the San Francisco Bay Area, with a new 25,000 sq ft facility in Alameda, California, where we routinely develop, optimize, and scale our AI-enabled continuous fermentation technology from bench through pilot scale, and subsequently deploy it at partner and commercial facilities worldwide.

We are seeking an experienced, independent, and collaborative Analytical Chemist/Scientist, Analytical Chemistry to join our growing Operations organization. In this role, you will play a leading technical role in the technology transfer, adaptation, validation, and execution of analytical methods supporting Pow.

Bio’s customer programs.

You will work closely with internal teams and external partners to translate customer analytical protocols into robust, fit-for-purpose assays and ensure high-quality, timely delivery of analytical data across active projects. This role includes direct ownership of both routine and technically complex sample analysis, as well as responsibility for the day-to-day operation, maintenance, and troubleshooting of laboratory instrumentation.

With your industry background in analytical chemistry, you understand the importance of running a focused, reliable, execution-oriented operation. You hold yourself to high data quality standards, ensuring results are accurate, traceable, and clearly communicated. You are comfortable engaging with scientists and engineers to interpret data, investigate anomalies, and address issues transparently when they arise.

You have a genuine interest in analytical instrumentation and enjoy hands‑on troubleshooting, preventive maintenance, and continuous improvement of laboratory workflows. You are motivated to keep learning—expanding your method development capabilities, adopting new analytical platforms, and improving how analytical data supports fermentation and process development decisions. As an early member of Pow.

Bio’s Analytical Chemistry team, you will have a meaningful influence on how the function is built and how it supports our customers and internal stakeholders.

• Own day-to-day analytical operations, sample receipt, preparation, analysis, data review, interpretation, and timely reporting in support of Pow.
  
  Bio customer programs and internal development activities.
• Characterize the composition of defined and complex substrates, including feeds, media components, and raw materials, and assess how composition impacts fermentation performance and analytical outcomes.
• Analyze and interpret primary and secondary metabolites from microbial fermentations—including substrates, products, intermediates, and byproducts—using chromatographic and enzymatic-based methods.
• Operate, maintain, and troubleshoot analytical instrumentation, including liquid chromatography systems and automated biochemical analyzers (e.g., Gallery™), performing routine maintenance, diagnosing issues, and coordinating repairs or service as needed.
• Integrate data from multiple analytical platforms (e.g., LC‑RI, LC‑UV/DAD, enzymatic analyzers) to support fermentation understanding, mass balance closure, and process decision-making.
• Establish, implement, and monitor quality controls for analytical methods and data, including system suitability, standards, controls, trending, and documentation to ensure consistency, reliability, and comparability across projects and over time.
• Lead the development, adaptation, and improvement of analytical methods, including translating…