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Structural Biologist III

Job in Aliso Viejo, Orange County, California, 92656, USA
Listing for: Tempus
Full Time position
Listed on 2026-09-16
Job specializations:
  • Research/Development
    Research Scientist, Biotech Research
Salary/Wage Range or Industry Benchmark: 120000 - 170000 USD Yearly USD 120000.00 170000.00 YEAR
Job Description & How to Apply Below
## Structural Biologist IIIApply:
Ambry Headquarters:
Full time:
Posted Yesterday:
JR
** Compensation:**$120,000 - $170,000
** Role Overview
** The Structural Biologist III collaborates across biology, bioinformatics, software engineering, and clinical teams to design tools and methodologies leveraging biomolecular structural data to guide clinical decisions.
** Key Responsibilities
*** Provide structural biology support for variant analyses through structure-function relationship interpretation.
* Develop novel methods, protocols, and tools for structural modeling, molecular dynamics, and clinical variant assessment on internal platforms.
* Partner with statisticians and data scientists to validate algorithms and data collection workflows.
* Coordinate cross-functional efforts across Bioinformatics, R&D, and reporting teams for clinical research projects.
* Write testable, production-grade code adhering to SDLC standards and code review best practices.
* Maintain technical documentation, SOPs, and knowledge bases while mentoring junior staff.
* Direct and lead the structural team through both soft and explicit leadership ensuring timely project completion
* Support, inform, and educate leadership and stakeholders about project progress and blockers.
** Qualifications & Competencies
**
* Education:

PhD in computational biology, structural biology, biophysics, bioinformatics, or equivalent.

* Experience:

Minimum 5 years of R&D experience in computational structural biology or related fields, including at least 2 years of post-doctoral or industrial experience and 2 years management experience.
* Technical

Skills:

Fluency/proficiency in scripting/languages (Python, R, Perl, C/C++, Java, SQL) and bioinformatics/modeling software. Strong background in systems biology, molecular dynamics, and experimental techniques (X-ray, Cryo-EM).
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