Structural Biologist III

Compensation

$120,000 - $170,000

The Structural Biologist III collaborates across biology, bioinformatics, software engineering, and clinical teams to design tools and methodologies leveraging biomolecular structural data to guide clinical decisions.

• Provide structural biology support for variant analyses through structure-function relationship interpretation.
• Develop novel methods, protocols, and tools for structural modeling, molecular dynamics, and clinical variant assessment on internal platforms.
• Partner with statisticians and data scientists to validate algorithms and data collection workflows.
• Coordinate cross-functional efforts across Bioinformatics, R&D, and reporting teams for clinical research projects.
• Write testable, production-grade code adhering to SDLC standards and code review best practices.
• Maintain technical documentation, SOPs, and knowledge bases while mentoring junior staff.
• Direct and lead the structural team through both soft and explicit leadership ensuring timely project completion.
• Support, inform, and educate leadership and stakeholders about project progress and blockers.

• Education:
  
  PhD in computational biology, structural biology, biophysics, bioinformatics, or equivalent.
• Experience:
  
  Minimum 5 years of R&D experience in computational structural biology or related fields, including at least 2 years of post-doctoral or industrial experience and 2 years management experience.
• Technical
  
  Skills:
  
  Fluency/proficiency in scripting/languages (Python, R, Perl, C/C++, Java, SQL) and bioinformatics/modeling software. Strong background in systems biology, molecular dynamics, and experimental techniques (X-ray, Cryo-EM).

Ambry Genetics Corporation is a CAP-accredited and CLIA-licensed molecular genetics laboratory based in Aliso Viejo, California. We are a genetics-based healthcare company that is dedicated to open scientific exchange so we can work together to understand and treat all human disease faster. At Ambry, everyone is welcome. A career at Ambry Genetics is a chance to be part of a dynamic company that aims to improve health by understanding the relationships between genetics and human disease.

We earned our reputation as industry leaders by responsibly introducing cutting-edge genetic testing solutions and continually sharing what we learn with the global scientific community. At Ambry you will be learning, challenging yourself, and having fun while collaborating with teammates through the open exchange of ideas.

• Our outstanding benefits program includes medical, dental, vision, FSA, paid sick leave and generous paid time off (PTO) program.
• The Company reserves the right to make changes to the 401k plan from time to time.
• You can learn more about the benefits here.

Ambry Genetics is an Equal Opportunity Employer (EOE) and we maintain a drug-free work environment. The Company believes in second chance employment. Qualified applicants with arrest or conviction history will be considered regardless of their arrest or conviction history, consistent with local laws such as Los Angeles County Fair Chance Ordinance and the California Fair Chance Act. You do not need to disclose your criminal history or participate in a background check until a conditional job offer is made to you.

After making a conditional offer and running a background check, if the Company is concerned about conviction that is directly related to the job, you will be given the chance to explain the circumstances surrounding the conviction, provide mitigating evidence, or challenge the accuracy of the background report.

Ambry does not accept unsolicited resumes from individual recruiters, third party recruiting agencies, outside recruiters or…