Sr. Director, Enterprise Application Integration delivery

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.

McKesson is seeking an experienced leader to drive Enterprise Application integration delivery for a large-scale SAP S/4

HANA transformation program. This role will lead enterprise application integration strategy, planning, governance, and execution across critical business capabilities, ensuring successful migration, testing, cutover, and operational readiness. The successful candidate will partner with business, technology, system integrator (SI), middleware, data, and process teams to ensure high-quality delivery of integrations supporting pharmaceutical distribution, supply chain operations, and regulatory compliance requirements. This position requires strong technical program management expertise, executive stakeholder management, and experience leading complex transformation initiatives.

• Lead delivery of the enterprise integration portfolio for a SAP S/4
  
  HANA migration program, ensuring alignment with business objectives, timelines, and quality standards.
• Manage completion of interface inventory assessments and integration classification activities, including retire, reuse, rebuild, and new-build decisions.
• Own integration roadmaps, delivery plans, milestones, dependencies, and critical-path activities across program work streams.
• Drive execution of Wave-1 critical integrations and manage readiness activities through deployment.
• Hold system integrator, middleware, and delivery partners accountable for integration build, testing, defect resolution, and quality-gate achievement.
• Lead cutover planning, parallel-run strategy, integration risk mitigation, and decommissioning sequencing to support successful business transition.
• Partner with enterprise apps owners on data migration, application build, business process, and change management teams to proactively identify risks, manage dependencies, and support business case and ROM inputs.

Basic Requirements
- Degree or equivalent experience. Typically requires
13+ years of professional experience and 6+ years of diversified leadership, planning,communication, organization,and people motivation skills (or equivalent experience).

• 13+ years of progressive experience in enterprise integration delivery, IT program management, ERP transformation, or large-scale technology implementation programs.
• Experience in pharmaceutical distribution, healthcare, life sciences, or regulated supply chain environments.
• Technical knowledge of SAP, full stack App development, Data engineering, analytics
• Demonstrated expertise delivering enterprise integration initiatives involving EDI, B2B, APIs, e- commerce , analytical platforms, and cross-functional business processes.
• Experience managing system integrators, third-party vendors, and complex program dependencies.
• Strong background in program governance, risk management, executive communication, and stakeholder engagement.
• Experience developing and executing integration cutover, parallel-run, and deployment strategies.
• Experience presenting program status, risks, and investment recommendations to executive leadership.
• Ability to lead multiple work streams within highly regulated, complex environments while driving measurable business outcomes.

• Knowledge of DSCSA compliance, serialization, track-and-trace, and related regulatory requirements.
• Expertise in integration architecture governance and enterprise application ecosystems.
• Experience supporting mergers, acquisitions, divestitures, or large-scale business transformation programs.
• Familiarity with Agile, Waterfall,…