Bench Scientist

Bench Scientist

Location:

Andover - MA

Duration: 03+ years

The lab based role entails training on the state-of-the-art technology for intermolecular interactions and quantification of binding affinity of biotherapeutic drug to specific proteins in human biological matrices, possible labeling of biotherapeutic using radioisotopes and analysis of radioactive biological samples. This position requires strong analytical expertise, with background in engineering, protein biochemistry, or PK as a plus. The candidate will participate in all phases of laboratory operations including training on the technology, design of reagents, design of binding experiments, the development of sample preparation, assay execution, instrument maintenance, data analysis, summarization and reporting.

We are looking for a scientist passionate about learning and able to quickly apply new skills to the project needs.

• Design of protein reagents to be used in binding studies
• Run binding assays under minimal supervision; initiative in method development is expected
• Analysis of radioactive biological samples using scintillation counting or γ-counter
• Potential training on protein labeling using radioisotopes
• Independent daily operation, calibration, maintenance, and trouble-shooting the binding instrument
• Analysis of binding data and derive binding affinity using relevant software
• Handling of biological samples, specifically human and preclinical serum and tissues
• Summarize work and write reports

Required Skills:

· BS/MS level education in Analytical Sciences, Biochemistry, Chemistry, Physics, Engineering, Pharmacology or closely related fields required; advanced degree may be a plus

· Willing to work with radioactive material

· Industry experience in biopharma preferred

· Attention to detail is critical, and be able to handle very delicate and complicated instrument to produce reproducible data

· Strong analytical and biochemistry background is required. Good understanding of concepts of binding affinities is a plus

· Fast learner and be able to master running/maintaining the instrument after a short period of training

· Strong initiative for problem solving at a technical and intellectual level

· Excellent communication skills, both written and oral

· Works well both independently and as part of a team. Collaborative skills and effective partnering skills in a matrix-environment

· Strong data organization and analysis skills