Associate Engineer, RNA Material MS&T

Associate Engineer, RNA Starting Material MS&TResponsibilities

• Support commercial supply assurance for RNA starting materials by synthesizing nucleoside reference markers/standards.
• Execute development studies either independently or as part of a team under supervision.
• Assess scalability of proposed changes and execute experiments to mimic the impacts of operations at large scale.
• Participate in the technology transfer of improved processes to manufacturing sites.
• Cultivate a firm scientific understanding of Sarepta’s manufacturing processes to support process improvements, troubleshooting, and technology transfers.
• Perform synthesis and purification (chromatography) of nucleoside analogs to support both production and development goals.
• Contribute to collaborative efforts to characterize and manage the impurity profiles of intermediates.
• Use scientific judgment to determine likely source and fate of newly identified impurities and design experiments to test hypotheses as part of a cross‑functional team.
• Compile and interpret data, document study results, and present data and conclusions.
• Participate in vendor update meetings and provide input on ongoing vendor production projects.

• B.S. (required) in Chemical Engineering, Chemistry, or related discipline.
• 0–2 years related experience.
• Technical competence in organic chemistry and familiarity with analyzing and interpreting data from GC, LC‑MS, HPLC, NMR, and KF instrumentation.
• Experience running HPLC methods strongly preferred.
• Ability to handle a multi‑task workload and perform effectively under deadlines.
• Strong written and verbal communication skills.
• Strong interpersonal skills and attention to detail.
• May require