Postdoctoral position in Medicinal Chemistry Cancer Drug Discovery

Postdoctoral position in medicinal chemistry for cancer drug discovery

Postdoctoral position in medicinal chemistry is available in the laboratory of Prof. Tomasz Cierpicki, University of Michigan, Ann Arbor, to synthesize small molecule inhibitors for targeted therapies in cancer. We are seeking highly motivated synthetic organic chemists or medicinal chemists to join a comprehensive drug discovery program. Dr. Cierpicki lab is conducting highly interdisciplinary research focused on pre‑clinical development of novel anti‑cancer drugs, which covers medicinal chemistry, structural biology, biochemical and biophysical assays, biological and animal studies.

We have a strong team of synthetic chemists to support our drug‑discovery efforts. The successful candidate will be involved in designing and synthesis of small molecule inhibitors as potential anti‑cancer agents with a major focus on synthesis of heterocyclic compounds targeting protein‑protein interactions relevant to cancer. The duties will include design and synthesis of new analogues of existing leads to develop biologically active compounds for testing in cancer cells and animal models of cancer.

The candidate must be independent in designing synthetic routes, solving challenging synthetic problems, and efficient in synthesizing targeted molecules, including multi‑step synthesis.