Research Laboratory Tech Sr

Who We Are

The Department of Human (DHG) Genetics at Michigan Medicine is recognized as the first dedicated human genetics department in the United States. The DHG is one of nine basic science departments in the Medical School with primary missions of teaching and research devoted to advancing the fields of genetics and genomics to further our understanding of biology and human disease. The Department is growing as faculty are presently being recruited.

We enjoy social functions as a Department, including a yearly department picnic and a yearly department retreat.

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally.

Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

The laboratory of Agnieszka Lukaszewicz, in the Department of Human Genetics at the University of Michigan Medical School, is seeking a highly motivated senior research laboratory technician. The laboratory studies germline de novo mutations, with a focus on: (1) spectrum of de novo structural and copy number variants at meiotic DNA double-strand breaks in mice and humans, (2) determining molecular mechanisms driving de novo mutations in meiosis, (3) determining the impact of structural variation at recombination hotspots on genome stability.

This is an excellent position for a recent college graduate interested in gaining a few years of research experience before applying to graduate school. The position is thus an excellent opportunity to have regular and direct hands-on training from a PI and determine whether they are interested in pursuing a graduate degree.

The position is heavily focused on laboratory research, with a smaller amount of effort devoted as the lab manager for laboratory support/maintenance.

The selected applicant will be involved in well-defined research projects and is expected to make original scientific contributions, as well as interpret and analyze results. The position will heavily focus on mouse molecular genetic techniques.

Experimental responsibilities will include, but are not limited to, the following:

• Designing and performing PCR assays
• Mouse husbandry
• DNA extraction, subcloning, and genotyping
• Library preparation for next generation sequencing
• Fluorescence microscopy
• Data analysis using a variety of software programs
• Preparation of data for presentation
• Training of new lab members and functional supervision for undergraduate students

Non-experimental responsibilities will include, but are not limited to, the following:

• Purchasing of lab supplies and equipment as authorized
• Managing lab safety program and compliance with animal protocols
• Maintenance of lab equipment

• Bachelor's degree in biology, genetics, or a related area of study
• 1 year of undergraduate wet lab research experience
• Willingness to work with mouse model system
• Experience with PCR assays
• Experience with DNA extraction
• Knowledge and understanding of laboratory safety protocols including biological and chemical safety
• Ability and motivation to learn new experimental approaches and safety protocols, and analyze and present data Excellent teamwork and communication skills

• 2 years or more of undergraduate laboratory experience
• Experience with mouse husbandry
• Experience with Western blotting
• Experience with research data analysis
• Experience in training students and others on lab safety and on the application of new techniques

Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world's…