Protocol Coordinator

COG Research Foundation, LLC is a California 501(c)(3) entity founded in 2024 to serve as a fiscal sponsor for research programs, providing legal, fiduciary, and administrative oversight.

COG is a member of the National Cancer Institute (NCI) National Clinical Trials Network (NCTN) and is the world’s largest organization devoted exclusively to childhood and adolescent cancer research. It unites over 13,500 experts in more than 220 leading children’s hospitals, universities, and cancer centers across the United States, Canada, Australia, New Zealand, and Saudi Arabia, conducting more than 50 active clinical trials with approximately 9,500 participants registered each year.

The Protocol Coordinator (PC) serves as the protocol document specialist on the study team for all assigned COG trials. This position develops and maintains clinical research protocols, concepts, site communication memos, study training materials, and other study‑related documents under the scientific direction of the Study Chair and COG scientific committee leadership. The PC manages all internal and external review and approval processes throughout the trial, from early study concept to amendments, and coordinates with team members.

Full salary range for this position: $64,542 to $92,421 per year. The typical hiring range is $64,542 (minimum) to $78,482 (midpoint) based on 100% FTE. The starting salary is determined by candidate experience, skills, and budget availability.

The COG Research Foundation, LLC is a 100% remote employer; some travel may be required. Employees must reside within the United States.

• Serve as the protocol document specialist within the study team.
• Manage the development of all documents related to clinical research protocols in conjunction with the study chair, study committee, COG scientific committee leadership, and the study team.
• Review supplemental protocol documents, including lab manuals, pharmacy manuals, and Electronic Medical Record templates.
• Coordinate all internal and external review and approval processes throughout the trial, from early study concept to study closure.
• Work with the study committee to ensure protocol changes related to National Coverage Analysis feedback are incorporated.
• Establish and communicate clear study development goals and deadlines to study chairs, pharmacists, statisticians, research coordinators, and other committee members to ensure study activation within Operational Efficiency Working Group (OEWG) timelines.
• Manage weekly study development calls with the study committee to facilitate protocol development discussions and lead study activation kick‑off calls.
• Design experimental design schemas and therapy delivery maps consistent with the protocol’s treatment plan.
• Maintain internal study records in study folders and track important events through COG tracking applications as outlined in departmental SOPs.
• Work with Research Coordinators to review draft Case Report Forms (CRFs) for consistency with the protocol and ensure specific requirements of the protocol are met.
• Follow all steps of PC SOPs regarding study development and deliver a final research document that incorporates all clinical details needed to treat subjects and research elements needed to answer study questions.
• Work with the League Administrative Assistants to prepare e‑friendly study documents that contain appropriate bookmarks and active links for website posting.

• Communicate with and facilitate communication between study chairs, study committee members, scientific committee chairs, institutional CRAs, and other cooperative groups as necessary.
• Respond to and resolve queries; take the lead on resolving issues related to study documents.
• Track information on reported problems regarding consistency and/or clarity in open protocols and work with the study team, study chairs, and disease chairs to resolve problems and amend the document as necessary.
• Identify the need for website postings to communicate updates for studies and prepare documents for posting.
• Stay informed of upcoming projects by attending study/disease…