Research Scientist

Summary

This position is in the Protein Discovery Department (Scientific Innovation Office) and will report to the In Vivo Science Manager. We are seeking highly motivated and hands-on experienced In Vivo Scientist. The individual within this position will work with other members of Protein Discovery to support and execute in vivo studies involving mice and rats.

This is a high-visibility role requiring direct, daily hands-on work with mouse and rat dosing and monitoring, and data and samples collection from vivo studies. The successful candidate will be responsible for ordering animals and lab supplies, preparing and conducting in vivo studies in the lab, and collecting and organizing samples from executed in vivo studies before their transfer to internal or external research entities.

Additional responsibilities include but are not limited to reviewing IACUC protocols, analyzing and presenting in vivo data internally, and externally, and supporting in vitro studies when the need arises.

The position requires familiarity with IACUC regulations for animal research and excellent communication skills to work effectively with multiple teams within Protein Discovery. The ability to work in a fast-paced environment and adapt to changing priorities is essential. This role offers the opportunity to make a significant impact on our goal of developing new medicines for patients.

• Ability to independently identify actions required to support departmental objectives.
• Execute action plans independently, as part of a team, or as the lead for a departmental team.
• Reports project activities to immediate supervisor and within group meetings, capable of presenting technical data at team meetings.
• Independently prepares and edits procedures or technical reports, including data interpretation, suitable for regulatory submission.
• Independently prepares and effectively communicates technical results in cross-functional team settings.
• Independently applies sound scientific principles in development of solutions to complex technical problems.
• Capable of mentoring/training junior staff in relevant principles and/or guidelines.
• Independently designs, executes, and interprets results for scientifically complex experiments.
• Capable of directing others in study execution.
• Order animals and lab supplies necessary to execute in vivo studies.
• Perform mouse and rat in vivo dosing, including tail vein injection, oral gavage, intraperitoneal and other IACUC-approved routes.
• Set up in vivo study execution, prepare Excel spreadsheets for data collection and label tubes used to collect of an array of samples from terminal animals.
• Collect in vivo data at the bench using Excel spreadsheets and post and maintain gained data into appropriate and designed locations (e.g., Protein Discovery SharePoint).
• Carry out terminal surgery in rodents for blood and tissue collection in compliance with IACUC policies and regulations.

• Maintains laboratory facilities in accordance with company policies and industrial best practices.
• Provides support for research and developmental studies, clinical or commercial manufacturing as needed.
• Identifies, implements, and qualifies, as necessary, equipment to meet industrial best practices or achieve compliance with regulatory expectations.

• Ability to set and meet deadlines, multitask, and prioritize resources based on project needs.
• Capable of supervising a small team of junior scientists.
• Must have excellent written and oral communication skills.
• Demonstrates ability to apply diverse knowledge-base to novel areas.
• Demonstrates ability to creatively apply scientific principles in problem solving in potentially novel areas.
• Has considerable knowledge in professional field of specialization.
• Proficient with the use of MS Office software.
• The position requires PhD plus 0-2 years experience, MS plus 2-4 years experience, or Bachelors plus 4-6 years experience.
• Educational degrees must be relevant to position (e.g., Pharmacology, Biology, or Animal Science Biochemistry, Chemistry, or Toxicology).

Work is performed in a clinical and/or a laboratory environment. Exposure to biological fluids with potential exposure to infectious organisms. Exposure to electrical office equipment. Exposure to chemicals. Personal protective equipment required such as protective eyewear, garments and gloves. Frequently sits and bends neck for 4-6 hours per day. May stand and twist neck for 2-4 hours per day. Occasionally walks, bends and twists waist and squats.

Repetitive hand movement of both hands with the ability to make fast, simple, repeated movements of the fingers, hands, and wrists. Ability to make precise coordinated movements, of the fingers to grasp and manipulate objects. Moderate lifting of 15-30 lbs. with a maximum lift of 35 lbs. May reach above and below shoulder height. Color perception/discrimination, near vision and far vision correctable in one eye to…