Bioprocess Associate – Upstream

Aruna Bio is a clinical-stage biotech company advancing a new class of cell-free biologics — exosomes — for the treatment of central nervous system and neurodegenerative disorders. We're looking for a Bioprocess Associate 1 – Upstream to join our manufacturing team and support production of AB126, our lead therapeutic exosome candidate.

As an Upstream Bioprocess Associate I, you'll be executing established upstream production processes in a cGMP environment. We need someone with solid hands-on cell culture skills, disciplined documentation habits, and the ability to work independently within defined procedures.

• Perform upstream bioprocess workflows, including mammalian cell culture maintenance, per established protocols and cGMP standards
• Support and occasionally participate in downstream bioprocess workflows via basic supply preparations, formulations, and documentation
• Follow aseptic technique practices to preserve both research and clinical material integrity
• Aseptically prepare media and buffers for mammalian cell culture
• Operate production equipment (pipettors, balances, biosafety cabinets, incubators, autoclaves, microscopes, centrifuges, etc.) safely and per relevant protocols
• Maintain safety standards and lab upkeep (includes routine disinfections of bioprocessing spaces and certain equipment)
• Complete manual, cGDP-compliant documentation in batch records and forms with a high degree of accuracy

• Associate's degree with a minimum of 2 years of experience in a relevant field (e.g. biology, cell biology, biochemistry, bioengineering); or a bachelor's degree in a relevant field plus 1 year of relevant research experience
• Ability to maintain aseptic mammalian cell culture without contamination under moderate supervision.
• Working knowledge of basic chemical and biological safety procedures in a lab setting
• Excellent organizational skills and the ability to manage substantial technical data while keeping accurate documentation
• Strong attention to detail and time management, along with strong written and verbal communication skills
• Demonstrated ability to work independently with limited supervision, showing personal accountability
• Proficiency with primary Microsoft Office Suite tools (Outlook, Microsoft Word, PowerPoint, Excel)
• Ability to work cooperatively in a controlled environment (ISO 5, 7, and
  8) wearing clean room PPE for extended periods of time.
• Willingness to participate in a rotating weekend work and holiday schedule to perform primary cell culture maintenance tasks
• Hands-on industrial experience in a cGMP-compliant environment (Preferred)
• Previous experience with production-scale, aseptic mammalian cell culture (Preferred)