Bioinformatician II

Description

Overview

Tanaq Management Services (TMS) delivers professional, scientific, and technical services and information technology (IT) solutions to federal agencies in the health, agriculture, technology, and other government services. TMS is a subsidiary of the St. George Tanaq Corporation, an Alaskan Native Corporation (ANC) committed to serving Federal customers while also giving back to the Tanaq native community and shareholders.

About the Role

We are seeking a highly motivated Bioinformatician to support ongoing projects within public health and the federal government. The ideal candidate will have experience analyzing biological data in the areas of phylogenetics, molecular evolution, recombination analysis, and whole genome analysis. This position will involve supporting various laboratory projects, including the development of new vaccines, the study of infectious diseases, molecular epidemiology, and surveillance.

The successful candidate will have the opportunity to collaborate with various agencies and contribute to important research making a difference in the fight against disease.

The Bioinformatician is responsible for R-programming and experience in Matlab applications. This role will collaborate with scientists across various disciplines to extract meaningful insights from complex datasets and contribute to ongoing research projects.

This is a hybrid remote role based in Atlanta, GA. Some on-site work will be required at the client’s location in Atlanta, GA; the frequency will be determined by the client's needs.

• Assist in and lead projects in bioinformatics and computational biology.
• Provide data analysis support for sequencing requests through the Genome Sequence Lab.
• Conduct Bioinformatics Activities in support of several projects being undertaken in support of Global Polio Eradication Program.
• Perform assembly & Mapping activities, including genome assembly services for all sequencing platforms in the GSL (Sanger, Roche
  454, Illumina, Ion Torrent, MinION, and Pac Bio).
• Provide single platform assembly using software packages to include CLCbio, Celera Assembler, MIRA, velvet, and BWA.
• Conduct Genomics analysis such as SNP/indel detection, gene structure comparisons, gene absence/presence determination, and protein sequence comparisons utilizing software packages such as kSNP, BLAST, and custom software.
• Perform variant detection techniques, including Amplicon or Deep Sequencing, to determine consensus sequences.
• Conduct Metagenomics techniques to identify species of microorganisms from an uncultured DNA sample utilizing BLAST/Megan, metagenefinder, QIIME, MG-RAST, and 16S databases utilizing RDP and Green genes software packages.
• Provides legacy sequencing data retrieval.
• Analyze genetic sequencing data utilizing new methodologies or existing techniques that have been revised
• Collaborate on genetic analysis projects and studies with internal and external partners.
• Assist laboratory scientists (with varying levels of computational expertise) in the design and implementation of bioinformatics tools that support the automation of data analysis, especially for next-generation sequencing data and large data sets.
• Advise senior scientists on applying a variety of bioinformatics analysis tools used to compare and categorize polio and picornavirus isolates and virus populations.
• Request NGS Sequencing for Illumina MiSeq and Nova Seq;
  Pac Bio RSII and Sequel;
  Oxford Nanopore MiniON.
• This description does not encompass all tasks; employees may perform other related duties as required.

• Minimum 3 years of experience in the capacity of a bioinformatician.
• Experience with automation support; QMS & CLIA support; ELIMS integrations;
  Testing and curating new technologies, e.g., Nanopore; website development; communications and user experience
• Strong experience using applications such as BLAST/Megan, metagenefinder, QIIME, MG-RAST, and 16S databases such RDP and Green genes.
• Experience with Matlab.
• Experience with de novo assembly and reference mapping.
• Experience with Roche
  
  AVA, CLCbio, VIP, and Var Scan software packages
• Experience working for the federal government or in a public health setting preferred.
• Strong attention to detail.
• Ability to work independently and as part of a team in a fast-paced setting.
• Ability to work with a diverse interdisciplinary team.
• Excellent written and verbal communication skills.
• Effective organization skills.
• Advanced experience with comparative genomics methods, including SNP/indel detection, gene structure comparisons, gene absence/presence determination, and protein sequence comparisons.
• Ability to pass required Federal background screening, obtain and maintain government clearance.
• Must be legally authorized to work in the United States without the need for employer sponsorship, now or at any time in the future

• Experience maintaining epidemiological and laboratory data using SAS, or R, REDCap, Microsoft Access, Excel, Epi Info.
• Experience…