Instructor – Computational & Systems Immunology

Emory University is a leading research university that fosters excellence and attracts world-class talent to innovate today and prepare leaders for the future. We welcome candidates who can contribute to the excellence of our academic community.

Position Overview

The Laboratory of Biochemical Pharmacology (LOBP) and the Center for Viro Science and Cure in the Department of Pediatrics at Emory University are seeking a highly motivated and collaborative
Instructor
to join our dynamic, multi-disciplinary team. This position is designed for a scientist who will bridge computational biology and virology to lead research efforts to understand and modulate the immune response to viral infections. The ideal candidate will use their expertise in multi-omics data integration and systems immunology to identify novel therapeutic targets and biomarkers, directly supporting our mission to develop next-generation antiviral therapies.

Experience in protein expression and characterization is also desirable.

Key Responsibilities

• Lead Translational Research:Drive partially independent research projects that apply computational systems biology and integrative multi-omics (single-cell genomics, proteomics, metabolomics) to characterize immune cell states—particularly myeloid cells like neutrophils and monocytes—in the context of viral infections and chronic inflammatory diseases.
• Therapeutic Target Discovery:Utilize high-dimensional molecular data to discover and prioritize novel targets for antiviral and immunomodulatory drug development, with a focus on host-directed therapies that restore antimicrobial function and limit inflammation.
• Collaborative Science:Work closely with a team of virologists, medicinal chemists, modelers, structural biologists, pharmacologists, and clinicians. Translate complex biological hypotheses into actionable computational frameworks and contribute to multidisciplinary publications.
• Mentorship and Training:Mentor and train graduate students, postdoctoral fellows, and research staff in computational immunology, bioinformatics, and reproducible research practices.
• Scientific Communication:Play a key role in preparing manuscripts for high-impact journals and contributing to grant applications.

• Professional Development:Actively represent LOBP at national and international conferences to present research findings, build collaborative networks, and enhance the visibility of the laboratory's work. The successful candidate will also be expected to write and submit independent grant proposals, progressively transitioning toward greater scientific independence and external funding.

Required Qualifications

• Ph.D. in Bioinformatics, Biomedical Sciences, Computational Biology, Immunology, or a closely related field.
• At least 5 years of relevant experience as a post-doctoral fellow and/or Research Scientist
• Experience in protein purification and characterization.
• A strong publication record in computational immunology, integrative multi-omics, or translational bioinformatics, as demonstrated by peer-reviewed publications.
• Proven expertise in analyzing and integrating high-dimensional datasets (e.g., single-cell RNA-seq, proteomics, metabolomics).
• Proficiency in programming languages (R, Python) and bioinformatics tools for differential expression, pathway enrichment, and network analysis.

Preferred Qualifications

• Postdoctoral experience in a relevant field, with a focus on immunology, virology, or host-pathogen interactions.
• Experience in therapeutic target identification and biomarker discovery.
• A demonstrated commitment to team science, reproducible computational infrastructure, and mentoring.
• Experience with high-performance computing and machine learning approaches for immune state…