Postdoctoral Fellow- MCG-Pharmacology & Toxicology

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Location

Augusta University

Our Health Sciences Campus: 1120 15th Street, Augusta, GA 30912

Our Summerville Campus: 2500 Walton Way, Augusta, GA 30904

College/Department Information

Pharmacology and Toxicology was established as a department at the Medical College of Georgia in 1943. Originally developed to discover how remedies and poisons effected man, modern pharmacology lays the groundwork to discover and develop future generations of therapeutics. Pharmacology's scope has broadened to include computer-assisted drug design; genetic screens; protein engineering; and new drug-delivery vehicles like viruses and artificial cells.

The department's history of accomplishments includes the discovery of the adrenergic receptor subtypes-alpha and beta which led to developing several drugs used to treat cardiovascular disease. Cardiovascular and neuroscience studies are the focuses of the department's research programs. Raymond P. Ahlquist, working in this Department, first defined alpha- and beta-adrenergic receptors in 1948. This discovery eventually led to the development of beta blocker drugs for hypertension and heart disease.

Job Summary

The main focus of Dr. Kaddoumi's Laboratory is to investigate the contribution of cerebrovascular dysfunction to the pathogenesis of Alzheimer's diseases and related dementias (ADRD) and to develop therapeutic strategies to restore AD-associated dysfunctional blood-brain barrier (BBB) and improve cognitive function. For this postdoctoral position, applicants must hold a PhD, MD, or equivalent degree in a related field (neuropharmacology, neuroscience, neurochemistry, vascular biology).

A background in ADRD pathologies, and molecular and cell biology is required, with experience in CRISPR/Cas gene editing, IPSC differentiation, cell culture, and animal models. Candidates should have good written and oral communication skills, work effectively in a team environment, be highly organized, and have a documented record of research accomplishments.

Responsibilities

Responsibilities to include, but are not limited to:

Design, conduct experiments, analyze, validate, and present research data, contribute to manuscript preparation,…