Research Services Professional​/Research Lead

Research Services Professional/Research Lead

The Burger laboratory in the Colorado Program for Musculoskeletal Research, within the Department of Orthopedics, is seeking to fill the position of a Research Services Open-Rank Intermediate to Principal Professional. In the Burger lab, we are interested in early vertebrate development of the axial and lateral plate mesoderm using zebrafish and mice as models, as well as associated structural birth defects, such as spina bifida, or defects affecting the heart/blood/bone/kidney.

We are further interested in how the axial mesoderm develops into the intervertebral discs, and associated underlying molecular mechanisms, as well as intervertebral disc disease, such as IVD degeneration. The Research Services Principal Professional is expected to be the research lead for several ongoing projects, including design of experimental setup, data generation, and data interpretation.

Key Responsibilities:

• Conducting molecular biology experiments, such as, but not limited to: PCR, gateway cloning, restriction digest and T4 ligation, Sanger sequencing of plasmid vectors, RNA work, e.g. CRISPR guide RNA generation, mRNA generation, immunohistochemistry/fluorescence, Western blotting, RNA and genomic DNA collection from mouse for RNAseq and ATACseq experiments
• Work with different zebrafish mutant and transgenic strains, such as zebrafish husbandry/breeding, genotyping, embryo microinjections, drug/toxicant screens, phenotyping, etc.
• Ordering consumables and materials, etc.
• Maintaining laboratory area and equipment in working and clean condition
• Contributing to animal protocol writing
• Handling EHS requirements

Work Location:

Onsite – this role is expected to work onsite and is located in Aurora, CO.

Why Join Us:

The Department of Orthopedics' mission is to provide the highest quality patient care and advance the field of orthopedics through innovation in research and education. We place a high level of importance on achieving and maintaining a diverse environment that fosters excellence and rewarding opportunities. The Research Division in the Department of Orthopedics is comprised of a core group of orthopedic faculty pursuing cutting-edge basic, translational and clinical study of the musculoskeletal system.

Working in our group, you will benefit from a highly collaborative environment with numerous opportunities for career development. The University of Colorado offers a comprehensive benefits package that includes health insurance, life insurance, retirement plans, tuition benefits, ECO pass, paid time off – vacation, sick, and holidays and more.

Why work for the University? We have AMAZING benefits and offer exceptional amounts of holiday, vacation and sick leave! The University of Colorado offers an excellent benefits package including:
Medical:
Multiple plan options Dental:
Multiple plan options Additional Insurance:
Disability, Life, Vision Retirement 401(a) Plan:
Employer contributes 10% of your gross pay Paid Time Off:
Accruals over the year Vacation Days: 22/year (maximum accrual 352 hours) Sick Days: 15/year (unlimited maximum accrual) Holiday Days: 10/year Tuition Benefit:
Employees have access to this benefit on all CU campuses ECO Pass:
Reduced rate RTD Bus and light rail service There are many additional perks & programs with the CU Advantage.

Equal Employment Opportunity Statement:
The University of Colorado (CU) is an Equal Opportunity Employer and complies with all applicable federal, state, and local laws governing non-discrimination in employment. We are committed to creating a workplace where all individuals are treated with respect and dignity, and we encourage individuals from all backgrounds to apply.

Qualifications:

Minimum Qualifications:

• Intermediate Level: Bachelor's degree in biology, molecular biology, chemistry, genetics or related field One (1) year professional level wet lab research experience, including zebrafish work
• Senior level:
  Bachelor's degree in biology, molecular biology, chemistry, genetics or related field Two (2) years professional level wet lab research experience, including zebrafish work
• Principal level:
  Bachelor's degree in…