Laboratory Science Professional Entry Principal

Laboratory Science Professional (Open Rank: Entry Principal)

University of Colorado Anschutz

Department: Biochemistry & Molecular Genetics

Position #:  – Requisition #39551

Job Summary: Experience in mTORC1 signaling, metabolic regulation, membrane remodeling, and cryo-electron microscopy (cryo-EM) is sought for the Cui Lab.

• Experimental Execution: Conduct molecular biology workflows including cloning, mutagenesis, plasmid preparation, protein expression and purification using insect or mammalian systems.
• Cell Culture Management: Maintain and manipulate mammalian cell lines, ensuring consistent quality for biochemical and structural studies.
• Structural Biology Support: Assist in preparation of samples for cryo-EM and cryo-ET, support maintenance of specialized laboratory equipment.
• Lab Operations: Coordinate daily lab activities, order supplies, manage chemical/biological inventories, maintain shared databases.
• Safety & Compliance: Serve as primary point of contact for Environmental Health and Safety (EHS) to ensure full regulatory compliance.
• Collaboration: Work closely with the PI and postdoctoral fellows to design and optimize experimental protocols.

Work Location: Onsite

• Medical:
  Multiple plan options
• Dental:
  Multiple plan options
• Additional Insurance:
  Disability, Life, Vision
• Retirement 401(a) Plan – employer contributes 10% of gross pay
• Paid Time Off:
  Accruals over the year
• Vacation Days: 22 per year (max accrual 352 hours)
• Sick Days: 15 per year (unlimited maximum accrual)
• Holiday Days: 10 per year
• Tuition Benefit:
  Employees have access on all CU campuses
• ECO Pass:
  Reduced rate RTD bus and light rail service

• Bachelor’s degree in biology, molecular biology, chemistry, genetics, or related field.

• Bachelor’s degree in biology, molecular biology, chemistry, genetics, or related field.
• One year professional‑level research experience.

• Bachelor’s degree in biology, molecular biology, chemistry, genetics, or related field.
• Two years professional‑level research experience.

• Bachelor’s degree in biology, molecular biology, chemistry, genetics, or related field (or equivalent experience).
• Three years professional‑level research experience.

• Master’s degree in biology, molecular biology, chemistry, genetics, or related field.
• More than one year of experimental or wet laboratory experience.
• Hands‑on experience with protein purification (FPLC/AKTA) or biochemical assays.
• Demonstrated ability to manage laboratory logistics and inventories in a startup or academic setting.

• Basic laboratory techniques, safety procedures, and protocols.
• Effective written and verbal communication.
• Ability to coordinate relationships with employee colleagues.
• Strong customer service orientation.
• Ability to interpret complex research protocols.

• Proficient laboratory techniques, safety procedures, and protocols.
• Effective written and verbal communication.
• Ability to coordinate relationships with employee colleagues.
• Strong customer service orientation.
• Ability to interpret complex research protocols.

• Advanced laboratory techniques, safety procedures, and protocols.
• Effective written and verbal communication.
• Ability to coordinate relationships with employee colleagues.
• Strong customer service orientation.
• Ability to interpret complex research protocols.

• Expert laboratory techniques, safety procedures, and protocols.
• Expert problem‑solving and analytical skills.
• Effective written and verbal communication.
• Ability to coordinate relationships with employee colleagues.
• Strong customer service orientation.
• Ability to interpret complex research protocols.
• Higher‑level knowledge of Structural Biology, Instrumentation, and Computational Biology.

• Entry: $46,274 – $58,861
• Intermediate: $50,357 – $64,054
• Senior: $54,440 – $69,248
• Principal: $62,606 – $79,635

University of Colorado Anschutz is an Equal Opportunity Employer and complies with all applicable laws. We encourage applicants from all backgrounds.

We provide reasonable accommodations to applicants with disabilities throughout the application process.

Background investigations will be conducted for all prospective employees.

Vaccination against COVID‑19 and other vaccine‑preventable diseases is strongly encouraged.

Screening Begins: April 15, 2026