Post Doctoral Research Fellow

Post Doctoral Research Fellow – University of Colorado Anschutz Key Responsibilities

• Design and conduct preclinical radiopharmaceutical research studies across multiple stages of development.
• Perform radiolabeling procedures and quality control testing to ensure compound integrity and performance.
• Execute bioconjugation and in vitro characterization studies to evaluate radiopharmaceutical properties.
• Develop and maintain mammalian cell cultures and tumor models for experimental research.
• Conduct PET/SPECT imaging, biodistribution, dosimetry, and therapeutic efficacy studies.
• Analyze tissues and investigate biological mechanisms underlying treatment response.
• Contribute to translational molecular imaging, radiopharmaceutical development, and cancer therapy research, leveraging prior radiochemistry or radiopharmaceutical therapy experience to build an independent research program.

• Training in translational radiopharmaceutical development, including study design, radiochemistry workflows, imaging and biodistribution studies, dosimetry, therapy response assessment, and regulatory‑style documentation.
• Opportunities to contribute to the development of new research directions, including independent project ideas aligned with the candidate's long‑term career goals.
• Mentorship in manuscript preparation, grant writing, fellowship applications, and career development awards.
• Opportunities to mentor graduate students, technicians, summer students, and other trainees.
• Opportunities to collaborate with clinicians, radio chemists, imaging scientists, cancer biologists, medical physicists, and industry partners.
• Funding and support to attend and present at national scientific meetings.

Onsite, Aurora, CO

• PhD, MD/PhD, PharmD/PhD, or equivalent doctoral degree in chemistry, radiochemistry, chemical biology, chemical engineering, biomedical engineering, pharmaceutical sciences, molecular imaging, cancer biology, molecular biology, or a related biomedical sciences field.
• Prior hands‑on experience with radiochemistry, radiolabeling, radioactive material handling, radiopharmaceutical therapy, radiotracer development, or closely related radiopharmaceutical research.
• A strong interest in cancer imaging, targeted radionuclide therapy, radiopharmaceutical development, or translational oncology.

• Experience with alpha‑or beta‑particle radiopharmaceutical therapy.
• Experience with radio labeled antibodies, antibody fragments, peptides, nanoparticles, small molecules, or pretargeted imaging/therapy systems.
• Experience with PET, SPECT, biodistribution studies, dosimetry, or quantitative imaging analysis.
• Experience with in vivo tumor models, including xenograft, orthotopic, metastatic, or patient‑derived models.
• Experience with in vitro cancer biology assays, including 2D or 3D cell culture, organoids, viability assays, receptor binding/internalization assays, clonogenic survival, DNA damage assays, immunofluorescence, flow cytometry, western blotting, or IHC.
• Experience with bioconjugation, antibody characterization, protein chemistry, size‑exclusion chromatography, HPLC, stability testing, or related analytical methods.
• Experience analyzing and visualizing data using Graph Pad Prism, ImageJ/FIJI, Flow Jo, Python, R, Cell Profiler, or related platforms.
• Experience preparing manuscripts, fellowship applications, grant applications, presentations, SOPs, IACUC protocols, radiation safety documentation, or regulatory‑style reports.
• Evidence of scientific leadership, collaboration, mentorship, and ability to move projects from experimental planning through publication.

• Demonstrated ability to design, execute, analyze, and interpret rigorous experiments.
• Strong written and oral communication skills.
• Ability to work independently while contributing to a collaborative, multidisciplinary research team.

University of Colorado offers a comprehensive benefits package for Post‑Doctoral Fellows, including health plans, retirement contributions, paid leave, and support for professional development. Detailed benefit information is available through the university’s resources for Post‑Doctoral Fellows.

The University of Colorado is an equal‑opportunity employer and complies with all applicable federal, state, and local laws governing nondiscrimination in employment. The university is committed to creating a workplace where all individuals are treated with respect and dignity, and encourages individuals from all backgrounds, including protected veterans and individuals with disabilities, to apply.

The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. Background investigations are conducted for all prospective employees.