Research Services Principal

University of Colorado Anschutz Medical Campus Department:
Anesthesiology Research Services Principal Professional – Laboratory Sciences

Position # – Requisition #40885

iC42 Clinical Research & Development combines quantitative massspectrometry, metabolomics, and proteomics under one roof, a combination that makes it a unique facility and a CU Medicine site of clinical practice. As a Principal Professional, you will lead LC‑MS/MS analytics for pre‑clinical and clinical studies, including work that supports national multi‑center trials, in a laboratory that is cGLP‑compliant, CAP‑accredited, and CLIA‑certified.

Day to day, you will develop and validate HPLC and LC‑MS assays, guide study design and data analysis through manuscript preparation, and serve as a resource to principal investigators across a range of research disciplines. You will also provide informal leadership to team members, including workload guidance and mentoring.

• Set up and lead LC‑MS/MS analytics for pre‑clinical and clinical academic and regulatory studies
• Develop and validate HPLC and LC‑MS assays
• Provide laboratory science expertise and leadership in study design, data analysis, and manuscript preparation
• Independently review, develop, and implement new or modified laboratory techniques
• Maintain a GLP‑compliant laboratory environment
• Serve as a resource to principal investigators and other stakeholders
• Provide informal leadership to team members, including mentoring and workload guidance

Onsite – this role is expected to work onsite and is located in Aurora, Colorado.

iC42 Clinical Research & Development is a cutting‑edge bioanalytical resource and Service Center at the University of Colorado as well as a CU Medicine site of clinical practice. iC42 Clinical Research and Development combines quantitative massspectrometry (drugs, drug metabolites, endogenous compounds and large molecules), metabolomics (LC‑MS, GC‑MS and magnetic resonance spectroscopy‑based) and proteomics under one roof, which makes it a unique facility.

Moreover, iC42 Clinical Research and Development serves as a central laboratory for national multi‑center trials and coordinates and carries out clinical studies. The laboratory is compliant with the rules of good laboratory practice (cGLP, 21 CFR part 58), and it is accredited by the College of American Pathologists and CLIA certified.

We have AMAZING benefits and offer exceptional amounts of holiday, vacation and sick leave! The University of Colorado offers an excellent benefits package including:

• Medical:
  Multiple plan options
• Dental:
  Multiple plan options
• Additional Insurance:
  Disability, Life, Vision
• Retirement 401(a) Plan:
  Employer contributes 10% of your gross pay
• Paid Time Off:
  Accruals over the year
• Vacation Days: 22/year (maximum accrual 352 hours)
• Sick Days: 15/year (unlimited maximum accrual)
• Holiday Days: 10/year
• Tuition Benefit:
  Employees have access to this benefit on all CU campuses
• ECO Pass:
  Reduced rate RTD Bus and light rail service

There are many additional perks & programs with the CU Advantage.

• Bachelor's degree in biology, molecular biology, chemistry, genetics or related field
• Substitution: A combination of education and related technical/military/paraprofessional experience may be substituted for a bachelor's degree on a year for year basis.
• Three (3) years professional level research experience

Applicants must meet minimum qualifications at the time of hire.

• Master's degree in biology, molecular biology, chemistry, genetics or related field
• Four (4) years of experience in an experimental or wet laboratory
• Four years of experience with High Performance Liquid Chromatography (HPLC), preferably with HPLC – massspectrometry
• At least two (2) years of hands‑on experience working in a regulatory compliance‑compliant laboratory environment, ideally cGLP or cGMP.

• Applicants must be legally authorized to work in the United States without requiring sponsorship. We are unable to provide work visa sponsorship or employment authorization for this…