Executive Medical Director, Clinical Development Lead - Oncology - Lung & Head​/Neck Cancers

Position Summary

GSK is committed to transforming outcomes for people with cancer through innovative science, bold ambition, and strong partnerships across the healthcare ecosystem. The Clinical Development Lead (CDL) – Oncology operates at the asset level as the enterprise clinical strategy leader, accountable for defining the clinical strategy, scientific narrative, and decision framework across the asset lifecycle. The CDL serves as a full strategic partner within the Medicine Development Team (MDT) core quad, positioning Clinical Development at the centre of product strategy, governance, and investment decisions.

• Serve as the senior clinical strategy leader on the MDT core quad, representing the voice of Clinical Development in portfolio, governance, and investment decisions.
• Own the clinical and scientific narrative for the asset, acting as the recognised clinical authority whose leadership is synonymous with the asset’s clinical vision and development trajectory.
• Lead or co‑lead governance and investment discussions, translating clinical evidence and benefit–risk into strategic recommendations that inform portfolio prioritisation and resource allocation.
• Drive an integrated, end‑in‑mind approach to clinical strategy, moving beyond sequential development to ensure alignment across scientific, regulatory, and commercial considerations.
• Proactively engage enterprise stakeholders, including Medical Affairs, Integrated Evidence, Commercial, and Regulatory, to integrate perspectives, resolve trade‑offs, and align on product strategy.
• Define the asset‑level evidence‑generation strategy, including how clinical data is prioritised and integrated across development, regulatory, and lifecycle decisions.
• Operate across the full asset lifecycle, integrating insights across studies and functions to ensure a coherent and differentiated clinical position.

• Accountable for the strategic integrity and clinical direction of the Clinical Development Plan (CDP), ensuring it reflects asset‑level strategy and is delivered through programme teams.
• Own the integrated benefit–risk framework, ensuring alignment between clinical data, safety insights, and strategic decision‑making.
• Define the strategic direction and decision frameworks guiding study design and development approaches across the asset.
• Provide strategic direction to Senior Scientists on the content and scientific quality of CDP‑associated deliverables, ensuring execution aligns with asset‑level clinical intent.
• Leverage AI‑enabled insights, advanced analytics, and emerging data platforms to inform asset‑level strategic decisions, enhance the precision of programme direction, and strengthen the evidence base for governance and portfolio decisions.
• Ensure alignment between clinical strategy and programme‑level execution, maintaining clarity of clinical intent across teams.

• Serve as the default Clinical Development representative for Health Authority interactions, including scientific advice, regulatory meetings, and responses to queries.
• Provide strategic oversight and final clinical accountability for scientific communications derived from clinical data, including publications, congress presentations, and advisory materials.
• Represent Clinical Development across external engagements, including advisory boards, steering committees, IDMCs, and alliance partnerships.
• Synthesise integrated clinical insights and evidence trends to shape asset‑level strategic direction and inform governance decisions.
• Shape and influence clinical development standards, governance practices, and decision‑making frameworks across Oncology Clinical Development, ensuring consistency and quality at the programme level.

• Develop and mentor clinical development talent within the asset programme, ensuring the right people are in the right roles and that team capabilities are aligned with current and future development models.
• Contribute to talent calibration, succession planning, and resourcing…