Postdoctoral Researcher in Peptide Ionization and Fragmentation Mechanisms
Listed on 2026-02-16
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Research/Development
Research Scientist
We invite applications for a postdoctoral position in experimental mass spectrometry-based proteomics, focused on peptide ionization, charge state behavior, and fragmentation mechanisms in LC-MS/MS. .The project addresses fundamental limitations in current proteomics workflows, which rely almost exclusively on positive ion mode and therefore systematically under represent acidic peptides and selected post-translationally modified species. The overarching goal is to develop experimentally driven strategies, grounded in gas-phase ion chemistry, that improve peptide and proteome coverage by exploiting negative ion mode and advanced fragmentation methods.
Within this framework, the postdoc will drive method development and high-level experimental MS studies, including systematic investigations of charge state distributions, fragmentation behavior under collisional- and electron-based dissociation, and differentiation of peptide isoforms and PTMs using negative ion mode workflows.
Final date to receive applications:
March 4, 2026
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