Senior Scientist with Security Clearance

Job Family :
Scientist Travel Required :
None Clearance Required :
Ability to Obtain Public Trust

What You Will Do:

We are looking for a Senior Scientist to support the operational and research objectives of the National Institute on Aging (NIA) Intramural Research Program by supporting genomic, genetics, single-cell sequencing, and spatial transcriptomics research activities. This is a full-time position located in Baltimore, MD.
* Provide on-site scientific expertise, laboratory support, and data analysis support for genomic and genetics experiments conducted by NIA research staff.

* Organize, validate, and process samples for microarray, next-generation sequencing, spatial transcriptomics, and single-cell sequencing experiments.

* Use advanced scientific knowledge and laboratory skills to resolve complex genetics and genomics issues, provide experimental guidance, and conduct pilot studies to develop and improve laboratory techniques.

* Maintain an accurate inventory of samples, reagents, and consumables through tracking systems and databases; obtain vendor quotes and assist with purchasing requests for laboratory supplies, services, and equipment.

* Perform operational troubleshooting, calibration, software updates, and maintenance of specialized laboratory instruments while ensuring compliance with laboratory safety procedures.

* Support the planning, execution, troubleshooting, and analysis of single-cell and spatial transcriptomics experiments utilizing platforms such as Chromium X and Cyt Assist.

* Acquire, maintain, and support specialized laboratory instrumentation and evaluate emerging technologies, software, and methodologies for potential implementation.

* Design and conduct complex scientific experiments requiring broad knowledge of molecular biology, genomics, transcriptomics, and related scientific principles.

* Provide technical support and scientific guidance to laboratory staff on research projects, experimental design, assay development, and data interpretation.

* Establish, train users on, and help manage Laboratory Information Management Systems (LIMS) and Electronic Laboratory Notebooks (ELN).

* Maintain, calibrate, troubleshoot, and train staff on laboratory instrumentation, equipment, and associated software applications.

* Manage scientific resources, including reagents, frozen cell stocks, biological samples, and research inventories.

* Conduct bioinformatics and statistical analyses and prepare data for abstracts, scientific reports, manuscripts, and presentations.

* Maintain accurate and detailed electronic laboratory notebooks and research documentation.

* Collaborate with Principal Investigators and research staff to prioritize instrument usage and optimize laboratory operations.

* Coordinate with IT personnel regarding software, data management, instrument connectivity, and technology-related issues.

* Prepare technical reports, manuscripts, abstracts, posters, oral presentations, and other scientific communications.

* Present research findings at laboratory meetings, scientific conferences, symposia, and national scientific meetings.

* Support data management and sharing initiatives, including organizing and uploading datasets to repositories such as GEO, SRA, and MassIVE.

* Provide mentoring, training, and technical guidance to fellows, postdoctoral researchers, students, biologists, and junior scientists.

* Support scientific collaborations, grant-related activities, laboratory organization initiatives, and research program development.

* Provide scientific guidance to management and laboratory leadership through literature reviews, technical evaluations, and recommendations for research activities and equipment purchases.

* Incumbent capture, no other candidates were considered due to incumbent candidate identified. They meet the labor category requirements provided by the customer.

What You Will Need:

* Ph.D. in Neuroscience, Biology, or a related scientific field.

* Minimum of EIGHT (8) years of experience in genomics, genetics, molecular biology, and transcriptomics research.

* Hands-on background supporting single-cell sequencing and spatial transcriptomics workflows.

* Skilled in operating, maintaining, and troubleshooting specialized scientific instrumentation.

* Background conducting bioinformatics and statistical analyses of genomic and transcriptomic datasets.

* Proven ability to prepare scientific manuscripts, technical reports, presentations, and publication-quality figures.

* Knowledge of laboratory inventory management, research documentation, and electronic records.

* Proficiency with Microsoft Office Suite.

* Ability to train, mentor, and support researchers and laboratory personnel.

* Ability to maintain detailed electronic laboratory notebooks and research records.

* Must be able to obtain and maintain a Federal or DoD "public trust"; candidates must receive approved adjudication prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred. What…