Research Technologist (Oncology

Research Technologist

Dr. Mark Yarchoan and Dr. Vincent Lam are seeking to hire a Research Technologist with a BS/BA in Biology or Chemistry/Biochemistry or similar field with interests in immunology. The laboratories investigate immune-based approaches and neoantigen vaccination for prevention of acquired resistant advanced ALK+ non-small cell lung cancer. Under the supervision of Dr. Yarchoan and Dr. Lam, and the laboratory manager, individuals filling this position will participate in a wide range of translational cancer immunology research using primary patient-derived human samples and mouse models of hepatobiliary cancer.

The Research Technologist performs laboratory tasks and completes routine assays following common or established protocols and procedures.

• Perform clinical and/or research laboratory experiments by following common protocols independently or with instructions.
• Use basic science knowledge to learn techniques and methods of the lab.
• Gain problem-solving skills through progressive training, understanding of the research, and experience.
• Run lab tests and complete measurements.
• Identify and resolve common problems involved in routine assays.
• Increase skill base and knowledge of lab research and relevant assays.
• Train users in standard equipment operation and routine lab techniques and procedures.
• Set-up experiments based on defined standards.
• Collect project data.
• Prepare, test, and maintain standard laboratory equipment.
• Perform related laboratory maintenance, monitor inventory of supplies, clean equipment.
• Tissue culture, culture and maintain primary cells and cell lines using sterile technique.
• Perform in vitro assays to assess cellular responses and use gene editing techniques to generate transgenic cellular models.
• Maintain animal colonies and participate in mouse experiments including tumor implantation, tumor growth measurement, and harvesting of tumor and immune tissue.
• Perform immunological assays including flow cytometry, ELISA, and ELISPOT.
• Data analysis and interpretation:
  Analyze experimental data using statistical methods and relevant software tools, such as Graph Pad, and Flow Jo.
• Routine lab maintenance:
  Maintain lab equipment, reagent stocks, and necessary records.
• Other duties as assigned.

• Bachelor's Degree in Biology, Chemistry or related field
• Additional education may substitute for required experience, and additional related experience may substitute for required education beyond a high school diploma/graduation equivalent, to the extent permitted by the JHU equivalency formula.