Senior Systems Architect, Infrastructure & Operations

Lantheus (NASDAQ: LNTH) is the leading radiopharmaceutical-focused company, delivering life-changing science to enable clinicians to Find, Fight and Follow disease to deliver better patient outcomes. Headquartered in Massachusetts with offices in New Jersey, Canada, Germany, Sweden, Switzerland and United Kingdom, Lantheus has been providing radiopharmaceutical solutions for nearly 70 years.

Today, we're expanding our portfolio and pipeline across oncology, neurology and cardiology. Through recent acquisitions, along with strategic partnerships across the life sciences ecosystem, we are accelerating our efforts to advance precision medicine and improve patient outcomes around the world.

At Lantheus we are purpose-driven, and every employee plays a vital role in our success. We're dedicated to cultivating a high-growth, forward-thinking culture where innovation thrives and diverse perspectives drive meaningful progress.

Join us and be part of a company where your contributions make a real impact, because we know someone's health is in our hands.

We are seeking a visionary Senior Systems Architect to serve as the strategic backbone of Lantheus' modern infrastructure evolution. This isn't just a technical role. It's a partnership position where you'll shape the future of how we operate across on-premises, colocation, cloud, and disaster recovery environments. You'll be a key player who bridges the gap between deep technical mastery and business-driven innovation, transforming infrastructure from a cost centre into a competitive advantage.

In this pivotal role, you'll architect seamless experiences across Microsoft 365, hybrid virtualization platforms, and AI-driven automation while serving as a trusted advisor to leadership on technology investments that drive measurable cost savings. If you're a systems polymath who owns outcomes end-to-end, thrives at the intersection of security and productivity, and sees infrastructure as the foundation for business transformation, this is your opportunity to leave a lasting imprint on Lantheus' technological future.

This position is based in Massachusetts and requires a presence on-site (two/three) days per week, and is open to applicants authorised to work for any employer within the United States.

• Design and optimise infrastructure spanning on‑premises data centres (VMware ESXi, Nutanix AHV), colocation facilities, and multi‑cloud environments (Azure, AWS), ensuring seamless workload mobility and resilience across all tiers.
• Serve as the authoritative voice on M365 architecture, driving adoption of advanced capabilities including Microsoft Purview for data governance, eDiscovery for compliance, and Teams for enterprise collaboration.
• Govern and optimise collaboration platforms across Microsoft Teams, ensuring seamless integrations, security compliance, and adoption strategies that keep the workforce connected.
• Architect and govern identity infrastructure leveraging Okta for workforce identity, designing sophisticated Okta Workflows for automation, and implementing SAML/OIDC integrations that enable zero‑friction, zero‑trust access across the enterprise.
• Pioneer AI orchestration initiatives that eliminate toil, accelerate provisioning, and introduce intelligent automation across infrastructure operations, positioning Lantheus at the forefront of AIOps adoption.
• Own the end-to-end endpoint strategy encompassing Microsoft Intune for modern management, SCCM for legacy workloads, and Tanium for real‑time visibility, third‑party patching, and endpoint hygiene ure devices are secure, compliant, and optimised regardless of location.
• Collaborate hand-in-hand with the security team to prioritise, remediate, and validate vulnerability findings, embedding security‑by‑design principles into every infrastructure decision.
• Design and validate DR architectures that guarantee business continuity, leveraging enterprise backup solutions (e.g. Rubrik) for data protection, conducting regular fail‑over exercises, and maintaining RTO/RPO commitments that protect Lantheus' operations.
• Deliver strategic insights into infrastructure…