Senior Manager, Commercial Data Governance & Management

About Stoke:

Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine. Using Stoke's proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to selectively restore naturally-occurring protein levels. Stoke's first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study.

Stoke's initial focus are diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for Stoke's proprietary approach. Stoke is headquartered in Bedford, Massachusetts. For more information, visit

Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine. Using Stoke's proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to selectively restore naturally-occurring protein levels. Stoke's first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study.

Stoke's initial focus are diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for Stoke's proprietary approach. Stoke is headquartered in Bedford, Massachusetts. For more information, visit

The Senior Manager, Commercial Data Governance & Management will lead the governance, stewardship, and operational management of commercial data assets across the organization. Reporting to the Executive Director, Integrated Commercial Data Strategy & Launch Analytics, this role will establish and maintain governance processes, business rules frameworks, metadata management capabilities, and data catalog infrastructure needed to ensure commercial data is trusted, documented, discoverable, and fit for purpose.

This position serves as the lead for Commercial Data Governance, Data Stewardship, Business Rules Governance, Metadata Management, and Data Catalog Management.

• Develop and maintain the commercial data governance framework.
• Establish policies, standards, and operating procedures across commercial data domains.
• Facilitate governance meetings and align definitions, standards, and accountability.
• Drive resolution of data ownership, quality, and standardization issues.
• Promote adoption of governance standards across commercial functions.

• Serve as a lead steward for HCP, Account, Site of Care, Payer, Territory, Affiliation, and Organizational hierarchies.
• Partner with IT and MDM platform owners to support governance and maintenance of master data assets.
• Coordinate hierarchy maintenance, account alignment, affiliation management, and reference data governance.
• Lead identification and resolution of data quality issues.
• Establish monitoring processes and scorecards for data quality.

• Establish and maintain a centralized framework for documenting and governing commercial business rules.
• Create and maintain a repository supporting CRM, targeting, segmentation, patient services, market access, and analytics use cases.
• Develop…