Postdoctoral Researcher ERC-funded Project in Cancer Epigenomics/Epitranscriptomics
Listed on 2026-02-15
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Research/Development
Research Scientist, Clinical Research, Medical Science, Biomedical Science
Location: Town of Belgium
Organisation/Company Université Libre de Bruxelles (ULB) Research Field Medical sciences » Cancer research Researcher Profile Recognised Researcher (R2) Positions Postdoc Positions Final date to receive applications 15 Mar 2026 - 23:59 (Europe/Brussels) Country Belgium Type of Contract Temporary Job Status Full-time Offer Starting Date 1 Mar 2026 Is the job funded through the EU Research Framework Programme? Horizon 2020 Reference Number Is the Job related to staff position within a Research Infrastructure?
No
The Applied Cancer Epigenomics and Epitranscriptomics Group, headed by Dr. Jana
Jeschke, seeks a highly motivated
and skilled
postdoctoral researcher to explore new mechanisms of gene regulation in tumor heterogeneity.
Our group leverages state-of-the-art sequencing technologies to map changes in DNA and RNA modifications in human tumors. We utilize these changes to improve the stratification of cancer patients for outcome and treatment choice, to identify new targets for cancer therapy and to gain new insights into tumor biology.
You will join a young and international team of enthusiastic and dynamic scientists to perform research for our ERC-funded Epi Resist project. For this project, you will set-up the newest single-cell sequencing technologies, develop state-of-the-art breast cancer models of therapy resistance, work with epigenetic drugs and human specimens from clinical trials to study the role of the N6-methyladenosine (m6A) mRNA modification in the heterogeneity of breast cancers and their resistance to treatments.
T h is unprecedentedanalysis of the m6A methylome in breast cancer will allow you to gain invaluable newinsights into tumor evolution and to disclose uncharted disrupted pathways of chemo resistance that can be therapeutically exploite d. To r ealiz e this project , you require knowledge and skills related to m6 A mapping and mechanisms of tumor progression and therapy resistance.
Qualifications
We are seeking an enthusiastic and highly motivated scientist with a PhD degree in biomedical sciences and a strong background in cancer and preferably epigenetics/epitranscriptomics research. The position requires knowledge and experience with molecular and cellular biology techniques, particularly:
- Cell culture and in-vitro cancer models of therapy resistance
- RNA extraction, RT-qPCR, western blot, CRISPR, RNAi
- Phenotypic cancer assays (cell viability, cell proliferation with endpoint assays and /or live-cell imaging platforms (e.g. Incucyte))
- Sample preparation for single-cell RNA sequencing and preferably m6A/MeRIP sequencing
The successful candidate should further have a track record of:
- Research excellence as evidenced by publications
- Managing PhD students and technicians
- Working autonomous and in collaboration
- Excellent skills in spoken and written English
- Excellent organization, time management and interpersonal skills
Funding
The position is fully funded for 2 years. The salary will be commensurate according to experience following ULB’s pay scale. The start date is flexible: earliest 1st of March 2026, but no later than 1st of June 2026.
Our group is located at Erasme Campus of the Université Libre de Bruxelles (ULB) in Brussels, Belgium. We are part of Institut Jules Bordet, which has a long-standing track record of excellence in cancer research. We offer an excellent scientific environment that is committed to advancing responsible science through collaboration and inclusi on.
Application
Send yourcompelling cover letter along with your updated CV and three professional references by email directly to . All required documents should be combined into a single PDF document. The subject of the email:
Name. Do not include substantive information in the body of the mail. The Final date to receive applications is 15th of March 2026.
Research Field Medical sciences » Cancer research Education Level PhD or equivalent
Languages ENGLISH Level Excellent
Languages FRENCH Level Good
Research Field Medical sciences » Cancer research Years of Research Experience 1 - 4
Additional InformationFellowship (only for postdoctoral researchers arriving from…
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