Principal Associate Scientist-Scientist-Immunology Immunology Berkeley, CA

Immunologist Position At Prellis Biologics

Prellis Biologics is a dynamic startup revolutionizing immunology. We develop cutting-edge technologies to unlock the immune system's potential and drive innovation in therapeutic development.

We're seeking an enthusiastic and talented immunologist to play a pivotal role in advancing our groundbreaking platform. You'll collaborate closely with a multidisciplinary team to develop functional assays. This position is ideal for someone with strong experience working with immune cell systems and functional assays who enjoys bench work and contributing to data generation in a fast-paced, collaborative environment. You will work closely with scientists across biology and pharmacology to generate high-quality data that supports ongoing discovery efforts.

Responsibilities:

• Execute mechanism of action studies to elucidate target biology, pathway modulation, and disease relevance across in vitro and ex vivo models.
• Establish and employ novel techniques to characterize immune cell responses.
• Leverage your knowledge in immunology, cell biology, and molecular biology to contribute to the development of ex vivo immune processes.
• Perform in vitro and ex vivo cell culture
• Independently analyze, evaluate, and present data including but not limited to reporter-based functional assays, immune cell activation assays, apoptosis, and cell migration assays Principal
• Be hands-on in the lab (60-80% of the time) and thrive in a fast-paced environment.
• Collaborate and support coworkers in a matrixed environment
• Maintain accurate experimental documentation and contribute to protocol generation and laboratory best practices

Qualifications:

• PhD in immunology, cell biology, or a closely related field with 1+ years of relevant industry and/or postdoc experience. MSc in immunology, cell biology, or a closely related field with 4+ years of relevant industry experience.
• Extensive immunology lab experience, including flow cytometry (panel design, data acquisition, analysis, troubleshooting).
• Proficient in cell culture of both primary and immortal cell lines.
• Experience with ELISA/MSD, cytokine panels, and cellular signaling assays
• Expertise in experimental design, data analysis, and interpreting complex immunological data sets.
• Proficiency in primary cell isolation and culture, and in vitro assay development/execution to evaluate antibody candidates

Skills & Experience (Preferred):

• Knowledge of immune inflammatory processes and diseases.
• Project management expertise.
• Experience developing and implementing laboratory systems.
• Proficiency in Flow Jo, and Graph Pad Prism software.

About Prellis Biologics

At Prellis we integrate human biology with machine learning. We aim to revolutionize drug discovery by harnessing the power of the human immune system with tightly integrated machine learning to develop next-generation antibody therapeutics with unparalleled speed, precision, and safety. We are committed to empowering our pharmaceutical partners with access to the most promising fully human antibody candidates rapidly identified from the human immune repertoire, enabling them to bring life-changing treatments to patients faster than ever before.

Prellis Biologics is a pre-IPO biotech located in Berkeley, CA with a team-oriented, inclusive, and family-friendly culture. Our growing pipeline targets high unmet patient needs across therapeutic areas including metabolic disease, inflammation, and oncology. Prellis has raised funding from top investors, including Celesta, Khosla Ventures, SOSV, and Avidity Partners.

What You Can Expect Of Us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way.

Actual salary will vary based on several factors including, but not limited to, relevant skills, experience, and qualifications.

Benefits

• A competitive employee benefits package, including group medical, dental, and vision coverage, life and disability insurance, flexible spending accounts, and a 401(k) plan
• Stock-based long-term incentives
• Holiday package including a 1+ week winter shutdown
• Flexible work models, including remote and hybrid working arrangements, where possible

Equal Opportunity

Prellis Bio is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran, or disability status.

We believe diversity, equity, and inclusion need to be at the foundation of our culture. We work hard to bring together diverse teams — grounded in a wide range of expertise and life experiences — and work even harder to ensure those teams thrive in inclusive, growth-oriented environments supported by equitable company and team practices. All candidates can expect equitable treatment, respect, and fairness throughout the interview process.