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Bioinformatics Scientist

Job in Bethesda, Montgomery County, Maryland, 20814, USA
Listing for: Guidehouse
Full Time position
Listed on 2026-07-01
Job specializations:
  • Research/Development
    Data Scientist, Research Scientist
Salary/Wage Range or Industry Benchmark: 65000 USD Yearly USD 65000.00 YEAR
Job Description & How to Apply Below
** Job Family**  **:*
* Scientist

** Travel Required**  **:*
* None

** Clearance Required**  **:*
* Ability to Obtain Public Trust

*
* What You Will Do:

*
* We are looking for a Bioinformatics Scientist (Scientist V) in the IBIS Core to support the Vaccine Research Center (VRC) at NIAID through advanced computational biology and bioinformatics analysis. This position is a full-time position located in Bethesda, MD.

+ Implement and utilize workflows for next generation sequencing (NGS), including quality control (QC) and data analysis.

+ Initiate interdisciplinary collaborations with scientists from other organizations or institutions engaged in related research.

+ Provide scientific mentorship and guidance to students, postdoctoral fellows, technicians, and other staff in developing bioinformatics pipelines, particularly for spatial transcriptomics applications.

+ Provide programming and troubleshooting support to the Federal Government in the dissemination of research data.

+ Perform computational analysis of research datasets and identify trends and patterns.

+ Collaborate with multidisciplinary teams to design, analyze, manage, and interpret complex biological data.

+ Maintain detailed documentation of analyses and present results at laboratory meetings.

+ Develop novel computational programs and algorithms to facilitate discovery in large and complex datasets.

+ Evaluate and adapt bioinformatics techniques based on scientific literature, available resources, and research objectives.

+ Collaborate with experimentalists and computational scientists to develop new computational tools for scientific discovery.

+ Independently coordinate training of personnel on scientific, statistical, and programmatic software applications.

+ Present research findings at internal meetings, conferences, and seminars; contribute to scientific publications.

+ Attend scientific and programming meetings and maintain organized records of findings and discussions.

*
* What You Will Need:

*
* + Master's Degree in Bioinformatics, Computational Biology, or a related discipline.

+ A minimum of TWO (2) years of experience working with large, multimodal single-cell datasets.

+ Proficiency in Python and R programming languages.

+ Practical knowledge of and experience working with SLURM-managed high-performance computing (HPC) clusters.

+ Strong analytical, statistical, and problem-solving skills.

+

Experience with next generation sequencing (NGS) workflows and data analysis.

+ Ability to collaborate effectively in a multidisciplinary research environment.

+ Strong written and verbal communication skills, including presentation of scientific data.

+ Must be able to obtain and maintain a Federal or DoD "public trust"; candidates must receive approved adjudication prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred.

** What Would Be Nice To Have:*
* + Ph.D. in Bioinformatics, Computational Biology, or a related discipline preferred.

+

Experience with Xenium and/or Visium spatial transcriptomics platforms is preferred.

+ Familiarity with adaptive immune receptor repertoires and general immunology are beneficial.

The annual salary range for this position is $65,000.00-$.  Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs.

*
* What We Offer:

*
* Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.

Benefits include:

+ Medical, Rx, Dental & Vision Insurance

+ Personal and Family Sick Time & Company Paid Holidays

+ Parental Leave

+ 401(k) Retirement Plan

+ Group Term Life and Travel Assistance

+ Voluntary Life and AD&D Insurance

+ Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts

+ Transit and Parking Commuter Benefits

+ Short-Term & Long-Term Disability

+ Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities

+ Employee Referral Program

+ Corporate…
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