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Staff Scientist

Job in Bethesda, Montgomery County, Maryland, 20814, USA
Listing for: Guidehouse
Full Time position
Listed on 2026-08-11
Job specializations:
  • Research/Development
    Research Scientist, Biotech Research
Salary/Wage Range or Industry Benchmark: 98000 USD Yearly USD 98000.00 YEAR
Job Description & How to Apply Below
** Job Family**  **:*
* Scientist

** Travel Required**  **:*
* None

** Clearance Required**  **:*
* Ability to Obtain Public Trust

** What You Will Do**  **:*
* We are currently searching for a Staff Scientist to provide laboratory leadership and support services to perform interdisciplinary and collaborative research from bench to beside with the National Heart, Lung, and Blood Institute (NHLBI). This is a full-time, on-site opportunity in Bethesda, MD.

+ Combine biochemical, molecular, cellular, genetic, and quantitative approaches to investigate fundamental biological processes across a range of organisms, including fish, flies, mice, mammals, microbes, and viruses.

+ Gain an understanding on how cells sense, respond, and adapt to a variety of stress conditions, including nutrient deprivation, organelle damage, and pathogen infection.

+ Address how alterations in mTOR, TFEB, TFE3, and lysosomal function lead to human disease.

+ Seek to identify potential sites for therapeutic intervention suitable for further evaluation in translational and clinical research efforts.

+ Contribute to training and mentoring of all laboratory members.

** What You Will Need**  **:*
* + PhD with at least TWO (2) years of postdoctoral research experience in molecular biology, cellular biology, biochemistry, or related field OR

+ Master's degree with at least FIVE (5) years of intensive, hands-on research experience in molecular biology, cellular biology, biochemistry, or related field in lieu of PhD

+ Must have a mastery of Zebrafish models with skills such as husbandry, genetic crossing, and genotyping protocols.

+ Must have a have a strong publication record.

+ Experience working with other animal models.

+ Expertise in cellular biology and microscopy imaging.

+ Must be able to obtain and maintain a Federal or DoD Public Trust. Candidates must receive approved adjudication of their Public Trust prior to onboarding with Guidehouse. Candidates with an active Public Trust or existing suitability are preferred.

** What Would Be Nice To Have**  **:*
* + Advanced skills in light microscopy are strongly desired.

+ Knowledge of organelle cell biology (lysosomes, autophagy, intracellular trafficking), and a commitment to conducting related high-quality research.

+ Able to work independently and in a team setting.

+ Excellent verbal and written communication abilities.

+ Outstanding interpersonal and time management skills.

+ Demonstrated experience in staff training and mentoring.

The annual salary range for this position is $98,000.00-$.  Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs.

*
* What We Offer:

*
* Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.

Benefits include:

+ Medical, Rx, Dental & Vision Insurance

+ Personal and Family Sick Time & Company Paid Holidays

+ Parental Leave

+ 401(k) Retirement Plan

+ Group Term Life and Travel Assistance

+ Voluntary Life and AD&D Insurance

+ Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts

+ Transit and Parking Commuter Benefits

+ Short-Term & Long-Term Disability

+ Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities

+ Employee Referral Program

+ Corporate Sponsored Events & Community Outreach

+  annual membership

+ Employee Assistance Program

+ Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and  protection, etc.)

+ Position may be eligible for a discretionary variable incentive bonus

** About Guidehouse*
* Guidehouse is an Equal Opportunity Employer-Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation.

Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and…
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