Postdoctoral Fellow - Anatomy, Physiology & Genetics

Join the HJF Team!

Job Description

HJF is seeking a Postdoctoral Fellow responsible for initiating and carrying out research projects in collaboration with a research team studying mechanisms of cellular proteostasis coordination across mammalian tissues. This position will be in support of Department of Anatomy, Physiology & Genetics (APG) Dr. Rosarda's laboratory. The Rosarda Laboratory studies cell type specific patterns of stress pathway signaling using in vivo, in vitro, and bioinformatic approaches.

We use chemical-biological and chemical-genetic approaches for activating stress responsive signaling pathways in mammalian cells and murine models, high throughput and single cell sequencing strategies for defining stress pathway activity, and we are developing novel approaches for defining mechanisms of action for pharmacologic and metabolomic regulators of stress signaling. The Henry M. Jackson Foundation for the Advancement of Military Medicine (HJF) is a nonprofit organization dedicated to advancing military medicine.

We serve military, medical, academic and government clients by administering, managing and supporting preeminent scientific programs that benefit members of the armed forces and civilians alike. Since its founding in 1983, HJF has served as a vital link between the military medical community and its federal and private partners. HJF's support and administrative capabilities allow military medical researchers and clinicians to maintain their scientific focus and accomplish their research goals.

• Designs, develops, executes, and implements scientific research experiments and/or development protocols using in vitro and/or in vivo (murine) models with a strong level of independence.
• Develop new research methods and protocols as needed to advance the project.
• Investigates the feasibility of applying a wide variety of scientific principles and theories to potential inventions and products.
• Keeps detailed records of experimental design, protocol, results, and data processing.
• Will conduct in vivo animal studies (mice), including the administration of compounds via intraperitoneal (IP) injection.
• Analyze complex data, evaluate results, and summarize research findings effectively.
• Help mentor, train, and supervise junior team members, such as graduate or undergraduate students.
• Contribute to collaborative research projects both within the lab and with external partners.
• May perform other duties and responsibilities as assigned or directed by the supervisor. This may include attendance of and participation in required training for role.

• Doctoral degree required.
• Minimum of 0-5 years' experience required.

• Proven knowledge of appropriate scientific area and ability to analyze and interpret data.
• Experience with maintenance and manipulation of mammalian cell lines, including immortalized cell lines, human iPSCs, and/ or primary cells is required.
• Prior experience with standard molecular biology approaches (e.g. nucleic acid isolation, protein purification, western blotting) is required.
• Quantitative and statistical analysis experience required;
  Graph Pad Prism experience is beneficial.
• Knowledge of bioinformatics (e.g. RNA sequencing analysis) is preferred.
• Familiarity with standard scientific computing languages (e.g. R, python) is beneficial.
• Experience with animal husbandry, survival surgery, behavioral testing, and tissue processing is preferred.
• Performs specialized laboratory research utilizing experimental protocols with animals which involve specialized procedures is beneficial.
• Experience with microscopy, seahorse metabolic analysis, or flow cytometry is beneficial.
• Ability to obtain a T1/Public Trust Background Check.

• Lifting:
  Requires lifting materials up to 10 lbs.
• Ability to stand or sit at a computer for prolonged periods.

• This position will take place primarily in a laboratory setting.

• The annual salary pay range for this position is $52,800 - $75,000. Actual salary pay will be determined based on experience, education, etc.

• HJF offers a comprehensive suite of benefits focused on your health and well-being, from medical, dental, and vision coverage to health savings and retirement plans, and more.

Employment with HJF is contingent upon successful completion of a background check, which may include, but is not limited to, contacting your professional references, verification of previous employment, education and credentials, a criminal background check, and a department of motor vehicle (DMV) check if applicable. Any qualifications to be considered as equivalents, in lieu of stated minimums, require the prior approval of the Chief Human Resources Officer.

The contractor will not discharge or in any other manner discriminate against employees or applicants because they have inquired about,…