Staff Scientist

Staff Scientist

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

Axle is seeking a Staff Scientist to join our vibrant team at the National Institutes of Health (NIH) supporting the National Heart, Lung, and Blood Institute (NHLBI) located in Bethesda, MD.

Benefits We

Offer:

• 100% Medical, Dental & Vision Coverage for Employees
• Paid Time Off and Paid Holidays
• 401K match up to 5%
• Educational Benefits for Career Growth
• Employee Referral Bonus
• Flexible Spending Accounts:
• Healthcare (FSA)
• Parking Reimbursement Account (PRK)
• Dependent Care Assistant Program (DCAP)
• Transportation Reimbursement Account (TRN)

Position Information:

The purpose of this position is to support the research mission of NHLBI's Hematology Branch. The contractor shall design, conduct, analyze, and communicate original translational hematology research.

Additional Qualifications:

Certifications & Licenses:

• Ph.D. in Cell and Developmental Biology or related discipline
• Minimum 5 to 8 years of experience in scientific research including 3 to 5 years post-doctoral fellow at the NIH

Field of Study:

• Biology

Software:

• Microsoft Suite

Skills:

• Excellent analytical, organizational and time-management skills
• Proficiency in coordinating multiple research projects in a fast-paced environment.
• Strong communications skills, both oral and written.
• Proven track record of conducting state-of-the-art experimental techniques.
• Recognized academic excellence with numerous publications and research awards.
• Demonstrates outstanding scientific judgment, creativity, experimental rigor, troubleshooting ability, organization, and attention to reproducibility.
• Expertise in identifying and overcoming cellular barriers to therapeutic gene delivery.

Deliverables:

• Run Validation
  - Ad-Hoc
• Meet with lab members to present updates
  - Daily
• Work products and documents related to presenting findings at scientific meetings.
  
  - Ad-Hoc
• Well-documented experimental datasets; validated methods, protocols, and standard operating procedures; analyses and publication-quality figures
  - Bi-Weekly

Statement of Work Details:

• Analyze laboratory findings
  - Independently design and execute the scientific research projects and studies.
• Generate reproducible experimental data, validated methods, scientific analyses, protocols, and written products aligned with NHLBI research priorities.
• Perform confirmatory and mechanistic studies as needed, resolve technical limitations, integrate findings across experiments, and prepare the resulting work for peer-reviewed publication.
• Studies may use established cell models, primary human HSPCs, and approved in vivo models, as scientifically appropriate.
• Plan and administer biological research programs
• Identify, classify, and study structure, behavior, ecology, physiology, nutrition, culture, and distribution of plant and animal species
• Comply with all applicable NIH and NHLBI requirements for laboratory safety, biosafety, research integrity, information security, animal research, and research involving human specimens.
• Assists with performing basic laboratory experiments and procedures
• Monitor and observe experiments, recording production and test data for evaluation by research personnel
• Analyze experimental data and interpret results to write reports and summaries of findings
• Complete and extend studies evaluating baculovirus as a delivery platform for large DNA donor templates used in CRISPR-based targeted gene integration
• Provide hands-on scientific instruction and mentorship to students, postbaccalaureate trainees, fellows, and other laboratory personnel
• Lead laboratory research supporting the development of LNP-mediated in vivo genome editing of…