Scientist, Research Scientist, Clinical Research

Job Details Level: Experienced

Job Location:

National Institutes of Health (NIH) - Main Campus/Bethesda - Bethesda, MD 20892

Position Type:
Full Time Education Level: Bachelors Degree Salary Range: $ - $ Salary/year Travel Percentage:
None Job Shift: Day Job Category:
Public Health Position Objective:
The Scientist will provide support services to satisfy the overall operational objectives of the National Institute of Diabetes and Digestive and Kidney Diseases within the National Institutes of Health.

• Study basic principles of plant and animal life, such as origin, relationship, development, anatomy, and function
• Identify, classify, and study structure, behavior, ecology, physiology, nutrition, culture, and distribution of plant and animal species
• Plan and conduct biological research programs
• Develop and maintain liaisons and effective working relations with groups and individuals, agencies, and the public to encourage cooperative management strategies or to develop information and interpret findings
• Monitor biological technicians and technologists and other scientists 5
• Monitor and observe experiments, recording production and test data for evaluation by research personnel
• Analyze experimental data and interpret results to write reports and summaries of findings 4
• Collect and analyze biological data about relationships among and between organisms and their environment 3
• Coordinate the work of biological technicians and technologists and other scientists
• Prepares, organizes and maintains various lab samples, supplies, and equipment
• Maintain laboratory equipment
• Analyze laboratory findings
• Program and use computers to store, process, and analyze data Interpret research or operational data
• Record research or operational data
• Be responsible for the management of the Usdin Laboratory mouse colony. This work includes: maintaining stocks of essential mouse strainso coordinating the import of additional mice into the mouse colony and the export ofmice/mouse embryos/mouse sperm to other facilities as neededo ensuring the cryo-preservation and cryo-recovery of appropriate mouse lineso develop appropriate genotyping assays for new mouse lineso supervising the generation of new mouse lines both by CRISPR-mediated gene-editingof embryos and appropriate breeding strategies using pre-existing mutant miceo overseeing the generation of embryonic stem cell and embryonic fibroblasts derived from these animalso design and prepare animal study protocols and standard operation procedures (SOPs) 1
• Train new personnel in appropriate lab-approved SOPs including those in place for working with this animal colony 2
• Maintain and coordinate scientific equipment and make recommendations where necessary for the acquisition of new equipment
• Conduct research on the molecular mechanisms responsible for mutation and disease pathology in the Repeat Expansion Disorders, with a focus on the Fragile X-related disorder, Friedreich ataxia and GLC Deficiency.
• Perform research using genetic mouse and cellular models.
• Develop reagents, assays and methodology that contribute to the goal of moving all the projects in the laboratory forward.
• Maintain records of the experiments performed and the data acquired; update and maintain laboratory notebooks and databases.
• Perform scientific literature searches.
• Prepare reports on the experimental design notes and progress of research programs, studies and trials.
• Prepare experimental results, including images, blots, expression data, etc.
• Coordinate multiple projects concurrently in progress.
• Collaborate with other research staff to ensure continuity of progress.
• Participate in the weekly inter-group lab meetings and present research update as appropriate
• Produce presentation slides for meetings
• Prepare manuscripts and submit research papers to peer-reviewed scientific journals
• Attend scientific meetings and represent the lab in poster and oral presentations as opportunity
• Contribute to collaborative projects not only with other members within the lab, but also with other laboratories as opportunity arises
• Organize daily laboratory notebook on experiments
• Prepare biweekly updates on on-going experiments and tasks and present progress reports on assigned projects at group meetings
• Assist with Postbac recruitment, onboarding, and training
• Coordinate and maintain Lab Archives account at NIDDK
• Serve as the primary point of contact between the lab and the Institutional Animal Care and Use Committee (IACUC).
• Coordinate protocol…