Director, Portfolio Strategy Inflammation & Immunology

Locations

• United States
  - Massachusetts
  - Cambridge
• United States
  - Pennsylvania
  - Collegeville
• United States
  - New York
  - New York City

The Director of Portfolio Strategy for Pfizer’s Inflammation & Immunology (I&I) Early Commercial Business is an individual‑contributor role that shapes portfolio strategy and early commercial assessments across the I&I pipeline. Reporting to the Portfolio Strategy & Disease Area Lead, the Director leads strategic planning, trade‑off decisions, and AI‑enabled analytics to support long‑range portfolio thinking and business‑case development for high‑value pipeline opportunities.

• Develop long‑range commercial and portfolio strategy for the I&I Early Commercial Business, covering pipeline assets, lifecycle opportunities, and emerging disease areas.
• Synthesize scientific, clinical, commercial, access, competitive, and patient insights to inform portfolio priorities and trade‑offs.
• Assess near‑, mid‑, and long‑term opportunities to identify differentiated value creation for Pfizer’s I&I portfolio.
• Translate portfolio strategy into clear recommendations, implications, and decision materials for leadership and governance meetings.
• Monitor shifts in the I&I scientific and competitive landscape to identify emerging trends, risks, and development opportunities.
• Develop and refine early commercial assessments, product concepts, target product profiles, positioning hypotheses, market archetypes, and commercial opportunity assessments.
• Provide commercial input to clinical development, evidence generation, lifecycle, and indication sequencing discussions in partnership with cross‑functional colleagues.
• Help identify key value drivers, risks, uncertainties, and evidence needs that may influence future launch potential and portfolio value.
• Support commercial assessments of external innovation and Business Development opportunities relevant to the I&I portfolio.
• Contribute to opportunity assessments, valuation inputs, market‑sizing assumptions, competitive scenarios, and strategic fit evaluations.
• Partner with Business Development, R&D, Business Analytics & Insights, GASP, and Competitive Intelligence to pressure‑test assumptions and identify decision points.
• Develop executive‑ready materials communicating commercial opportunity, strategic rationale, risks, and portfolio implications.
• Partner with cross‑functional stakeholders to embed a commercial voice in early development and portfolio decisions and support preparation for governance and strategy meetings.
• Build trusted relationships across R&D, Medical Affairs, GA SP, BAI, Competitive Intelligence, Business Development, and Commercial Regions.
• Influence stakeholders without direct authority by aligning on insights, strategic choices, and portfolio implications.
• Use AI‑enabled tools to support scientific and competitive landscape synthesis, market insight generation, scenario development, and strategy efficiency.
• Apply AI‑augmented approaches to accelerate analysis, identify patterns across complex data sources, and improve outcome quality and consistency.
• Embed responsible, compliant AI‑enabled practices into early commercial strategy, portfolio assessment, and decision‑support processes.
• Stay current on emerging tools and practices that strengthen commercial strategy development and portfolio decision‑making.

• Bachelor’s degree with ≥8 years of experience OR master’s degree with ≥7 years OR PhD with ≥5 years of experience.
• Experience in pharmaceutical, biotechnology, life sciences, strategy consulting, corporate strategy, or related fields.
• Strong strategic and analytical skills with the ability to synthesize complex scientific, clinical, market, access, and competitive information into clear recommendations.
• Experience supporting portfolio strategy, early commercial assessment, business‑case development, opportunity assessment, or cross‑functional strategic planning.
• Demonstrated ability to manage multiple priorities and deliver high‑quality work in a matrixed environment.
• Strong communication, organization, problem‑solving, and stakeholder‑management skills.

• Experience in Inflammation &…