Senior Scientist - Medicinal Chemistry

Work Your Magic with us! Start your next chapter and join EMD Serono.

Ready to explore, break barriers, and discover more? We know you've got big plans - so do we! Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet.

That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.

• Strong technical background in nucleoside chemistry, peptides and small molecules
• Implement modern peptide chemistry and conjugation methodologies to accelerate optimization of miniprotein drug development.
• Design and execute receptor expression profiling, ligand‑receptor binding, internalization, and trafficking assays.
• Collaborate with cross‑functional teams including computational chemistry, biology, and pharmacology to drive project success.
• Method Development & Analytics:
  Establish high‑resolution analytical methods and pipelines. Develop and proceduralize in‑process testing and finished product QC using HPLC (SEC, IEX, IPRP) and LC‑MS.
• Innovation: drive innovation to improve circulating half‑life, tissue penetration, cellular uptake, and intracellular bioavailability of payloads.

• Ph.D. in Medicinal Chemistry, Synthetic Organic Chemistry, Chemical Biology, or related field, with a minimum of 5 years of industry experience.

• Strong track record of laboratory‑based innovation and problem‑solving in drug discovery including optimization of affinity, selectivity, drug properties, and PK profile.
• Proven expertise in the hands‑on peptide synthesis.
• Expertise in analytical characterization (e.g., SEC‑HPLC, NMR, IEX, IPRP, LC‑MS).
• Excellent communication skills for both technical and non‑technical audiences.
• Exceptional communication skills with the ability to translate complex data internally as well as with CROs.

We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!