Incident Response Engineer II

Incident Response Engineer II

Billerica, MA Hybrid

Quanterix is a global leader in ultra-sensitive biomarker detection, enabling breakthroughs in disease research, diagnostics, and drug development. Its proprietary Simoa technology delivers industry-leading sensitivity, allowing researchers to detect and quantify biomarkers in blood and other fluids at concentrations far below traditional limits. With more than 3,400 peer-reviewed publications, Quanterix has been a trusted partner to the scientific community for nearly two decades.

In 2025, Quanterix acquired Akoya Biosciences, The Spatial Biology Company, adding multiplexed tissue imaging with single-cell resolution to its portfolio. Together, the combined company offers a uniquely integrated platform that connects biology across blood and tissue-advancing precision medicine from discovery to diagnostics.

ROLE

SUMMARY:

Seeking a qualified Security Incident Response Engineer to join our growing organization and Information Security team. In this role you will work within the Security Operations team, reporting to the Director, IT Infrastructure and Security Operations. You will respond to security events, conduct analysis of threats such as malware and intrusion attempts, and provide security services to safeguard highly sensitive data.

You will work hands-on with detection systems and vulnerability analysis tools to respond to potential threats to Quanterix systems. You should be prepared to relentlessly resolve security issues by gathering and analyzing event data and conducting root-cause analysis. With your technical expertise, you will be solving security challenges at scale, working to protect the applications that support Quanterix and our fast-growing business.

We value broad and deep technical knowledge, specifically in the fields of forensics, malware analysis, network security, application security, threat hunting, and threat intelligence.

WHAT YOU'LL DO:

• As a SME, you will be responsible for leading incidents, investigations, and security initiatives
• Act as a security multiplier to help scale security incident response at Quanterix
• Prepare post-mortem reports of incidents and present findings to the broader team
• Create and maintain runbooks to ensure smooth handling of all security incidents
• Lead and participate in incident response tabletop exercises to validate and improve existing processes and procedures and train others on their roles and responsibilities during an incident
• Monitor and analyze security logs, using KQL queries in Microsoft Sentinel, to identify potential security breaches
• Build, refine, and maintain analytic rules, workbooks, hunting queries, and dashboards in Microsoft Sentinel to enhance detection and response capabilities
• Automate incident response and enrichment processes using Logic Apps, automation rules, and playbooks in Sentinel
• Assess vulnerabilities within the environment, conduct risk-based prioritization of vulnerabilities, and assist in remediation
• Lead and coordinate responses to cyber threats, including incidents identified in Microsoft Defender for Endpoint
• Build effective relationships with key stakeholders who own and support IT infrastructure, applications, processes, and operations
• Provide security engineering solutions and support during customer-facing incidents, proactively considering prevention of similar incidents in the future
• Assist in the development of pragmatic solutions that meet business requirements while maintaining an acceptable level of risk
• Identify and recommend solutions that improve or expand Quanterix incident response capabilities
• Work alongside Information Security and Infrastructure Operations engineers to improve security, reduce risk, and rapidly address incidents
• Evaluate the impact of current security trends, advisories, publications, and academic research to Quanterix, coordinating responses as necessary across affected teams
• Stay current with the rapidly changing threat landscape, continuously improving detection and response methods
• Participate in an on-call rotation
• Other duties as needed

BASIC QUALIFICATIONS:

• Bachelor's in computer science, information security, or equivalent…