IT Principal Business Application Architect

IT Business Applications Architect

Billerica, MA (Hybrid)

Quanterix is a global leader in ultra‑sensitive biomarker detection, enabling breakthroughs in disease research, diagnostics, and drug development. Its proprietary Simoa technology delivers industry‑leading sensitivity, allowing researchers to detect and quantify biomarkers in blood and other fluids at concentrations far below traditional limits. With more than 3,400 peer‑reviewed publications, Quanterix has been a trusted partner to the scientific community for nearly two decades.

In 2025, Quanterix acquired Akoya Biosciences, The Spatial Biology Company, adding multiplexed tissue imaging with single‑cell resolution to its portfolio. Together, the combined company offers a uniquely integrated platform that connects biology across blood and tissue‑advancing precision medicine from discovery to diagnostics.

Quanterix is seeking a Principal Business Applications Architect (Systems) to lead the strategy, design, and transformation of our enterprise applications landscape. This high‑impact role shapes how our core platforms—Infor Syteline 10, Salesforce Sales Cloud, Salesforce Service Cloud, Pardot, Tableau, and Microsoft Power BI—operate today while architecting our transition to Oracle Fusion Cloud over the next 12–18 months. As a Principal‑level individual contributor, you will partner directly with executive leadership to align technology, data, and business processes to enable scale, efficiency, and growth.

• Own the Business Architecture Landscape for business applications across ERP, CRM, and analytics
• Lead the end‑to‑end architecture and migration strategy to Oracle Fusion Cloud
• Drive Business Process Engineering & re‑engineering (BPE/BPR) across Finance, Supply Chain, Sales, Service, and Marketing
• Design scalable, integrated solutions across Salesforce and ERP ecosystems
• Establish architecture standards, governance, and integration patterns
• Partner with business leaders to translate strategy into systems and process solutions
• Enable data‑driven decision making through strong data and analytics architecture
• Mentor internal teams and influence system integrators and vendors

• 15+ years of related experience with a Bachelor’s Degree in Computer Science, Information Systems/Information Technology, Software Engineering or Business Administration (focus on Information Systems or Operations)
• 12+ years of experience with a Master’s Degree in Information Systems/Information Technology, Computer Science or Business Administration (MBA, especially with Operations, Strategy, or Technology focus)
• 12+ years of experience in Enterprise or Solutions Architecture

• Experience with Oracle Fusion Cloud implementations
• Background in Life Sciences, Diagnostics, or Healthcare
• Familiarity with regulated environments (FDA, SOX)
• Certifications (TOGAF, Salesforce Architect, Oracle Cloud)
• Proven success leading ERP transformations (Oracle, SAP, or similar)
• Strong experience with Salesforce ecosystem and enterprise BI tools
• Deep expertise in Business Process Engineering and Re‑Engineering
• Experience designing end‑to‑end, integrated enterprise solutions
• Strong knowledge of integrations (APIs, middleware, iPaaS) and data architecture
• Ability to influence senior stakeholders and drive cross‑functional alignment

• Travel 10%
• Strategic thinking with the ability to align enterprise systems to business growth and operational efficiency
• Ability to simplify complex system landscapes and communicate effectively with non‑technical stakeholders
• Strong collaboration and influencing skills across Finance, Commercial, Manufacturing, and Scientific teams
• Problem‑solving mindset with focus on scalable, integrated solutions
• Ability to manage competing priorities in a fast‑paced, evolving environment
• Attention to detail with a strong focus on data integrity and system reliability
• Continuous improvement mindset with focus on automation and optimization
• High ownership and accountability for architectural decisions and outcomes

• Lead a high‑visibility…