Associate Director, Internal Audit

Job Overview

The Associate Director of Internal Audit will support the development and execution of a risk-based audit plan to evaluate and improve the effectiveness of Vertex’s risk management, control and governance processes. The role reports to the VP, Chief Audit Executive (CAE) and assists in implementing departmental strategy, contributing to annual functional goals and overseeing portions of the SOX testing program.

• Maintain strong knowledge of Vertex’s core business and assist in developing a risk and control assurance program aligned with company objectives and risk appetite.
• Contribute to the development of departmental strategy, audit committee reporting and departmental initiatives such as data analytics, trend reporting, etc.
• Build collaborative relationships with Vertex leaders to promote understanding of risk, control and governance.
• Direct project team (managers, supervisors, staff) in the performance of audits and special requests such as investigations, and oversee execution of assigned portions of the audit plan.
• Ensure project planning, fieldwork and reporting are of high quality and in accordance with professional and departmental standards.
• Critically evaluate issues identified during the audit process and corresponding business risk, develop recommendations to enhance controls and partner with the business to develop workable solutions.
• Provide coaching and development to junior team members; may have limited supervisory responsibilities.
• Identify, develop and implement improvements in departmental practices (reporting, policies, procedures, audit programs, computerized applications, etc.).
• Coordinate internal audit work performed by third-party providers as needed.
• Assist in driving efficiency in SOX testing and support external auditor reliance.

• Analyze pharmaceutical/biotech processes and recommend control improvements.
• Strong verbal and written communication skills; influence and collaborate effectively.
• Organized, deadline-driven and adaptable in a dynamic environment.
• Solid understanding of auditing concepts and ability to apply them to complex scenarios.
• Proficient in interacting with management and external auditors.

• Bachelor’s degree in accounting or related discipline; MBA preferred.
• CPA required.
• 8+ years of progressive audit experience or equivalent combination of education and experience.
• Experience in financial, operational, compliance and forensic audits.
• “Big 4” accounting firm and industry experience (Pharma/Biotech) preferred.
• Prior experience mentoring junior staff.

• Demonstrate curiosity and adaptability in a fast‑paced environment.
• Build strong partnerships across the business to drive meaningful change.
• Apply critical thinking and problem‑solving skills to complex challenges.
• Embrace Vertex’s core values: innovation, integrity, collaboration and patient‑centricity.

Hybrid‑Eligible or On‑Site Eligible. In this Hybrid‑Eligible role, you can choose to be designated as:
- Hybrid: work remotely up to two days per week; or
- On‑Site: work five days per week on‑site with ad hoc flexibility.

Pay range: $148,800 – $223,200 (base salary). The role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay in accordance with federal and state requirements. Total rewards include medical, dental, vision, paid time off, educational assistance, commuting subsidy, charitable donation match, 401(k) and more.

Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non‑discrimination for all employees and qualified applicants without regard to a person’s race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status or any characteristic protected under applicable law. Vertex is an E‑Verify Employer in the United States and will make reasonable accommodations for qualified individuals with known disabilities.