ProFound Therapeutics: Senior Director, Alliance Management & Business Development

Company Summary

Pro Found™ Therapeutics is discovering proteins hidden within the expanded human proteome to uncover novel drugs and drug targets, producing first-in-class medicines for a multitude of diseases. The company’s Pro Foundry™ Platform uses state-of-the-art protein detection technologies to systematically identify and validate proteins and dissect their therapeutic potential. The result is an ever-expanding database of tens of thousands of novel proteins, including their connectivity, functionality, and roles in health and disease.

Pro Found Therapeutics was founded in 2020 by Flagship Pioneering. For more information, please visit

We are seeking an experienced and strategic Senior Director of Alliance Management and Business Development to lead the expansion and optimization of our external partnerships. This individual will be responsible for identifying, structuring, and managing strategic alliances, collaborations, and business development opportunities that align with our company’s scientific and commercial goals.

You will work cross-functionally with internal R&D, legal, finance, and executive leadership, and externally with current and prospective partners to drive long-term value creation.

• Serve as the primary relationship manager for key external partnerships, ensuring strategic alignment and execution of joint activities.
• Drive governance activities, including leading Joint Steering Committees and other alliance-related forums.
• Monitor and report on partnership health, performance metrics, risks, and milestones.
• Resolve issues proactively and diplomatically to maintain productive relationships.

• Collaborate with scientific and commercial teams to develop business cases and deal structures.
• Manage due diligence processes with internal subject matter experts.
• Prepare compelling materials (pitch decks, term sheets, etc.) to support BD discussions and negotiations.

• Partner with executive leadership to refine the company’s partnership strategy.
• Maintain deep knowledge of market trends, competitive landscape, and emerging opportunities.
• Represent the company at industry conferences, investor meetings, and partnering events.

• Advanced degree in life sciences, business, or a related field (MBA, PhD, or equivalent preferred).
• 10+ years of experience in biotechnology or pharmaceutical business development, alliance management, or related roles.
• Demonstrated success in negotiating and managing complex partnerships and transactions.
• Deep understanding of drug development, commercialization, and scientific innovation in biotech.
• Strong leadership, communication, and interpersonal skills; proven ability to influence across functions and externally.
• Thrive in a fast-paced, entrepreneurial environment with a hands‑on approach.

• Flexible, personable team-player, able to think “out-of-the-box”; comfort with a fast-paced, small company environment, early‑stage IP building, and helping design experiments to optimally support IP filings.
• Proven ability to set and meet ambitious deadlines, handle numerous multifaceted legal issues, and see projects through to conclusion.
• Strong written and verbal communication skills and demonstrated ability to work collaboratively with both scientists and management.
• Ability to distill complexity and to communicate decisively with sound judgment