Associate Director, Heme Global Business Systems

Position Summary

We are seeking an Associate Director, Heme CGT Business Systems to lead global system strategy for CASGEVY.

• Own the product vision, roadmap, and prioritization for commercial capabilities supporting the Heme Franchise Partner with IT and regional stakeholders to translate business priorities into scalable tools, processes, and product enhancements.
• Drive cross-functional alignment across global commercial teams, external manufacturing, quality, and other enabling functions to support business objectives, governance, and effective decision‑making.
• Work closely with Quality to ensure appropriate GxP processes, controls, and requirements are understood and adhered to across relevant systems, tools, and processes.
• Lead change management efforts to support successful implementation, stakeholder engagement, and adoption of commercial capabilities across the organization.
• Drive continuous improvement and ongoing optimization of commercial capabilities to enhance planning, execution, and operational effectiveness.

• Demonstrated success working in cross‑functional, matrixed organizations with multiple stakeholders.
• Strong ability to simplify high‑level concepts into actionable insights and advise on digital maturity, digital transformation and system integrations to the site leadership team.
• Analytical problem‑solving and strategic planning abilities.

Bachelor's degree in a relevant discipline. Typically requires 8 years of work experience leading the delivery of customer‑facing digital programs to promote products and services to external customers, or the equivalent combination of education and experience. Experience in GxP regulated systems and related documentation, and GxP process and change management is highly preferred.

Boston, MA

Hybrid-Eligible or On-Site Eligible. In this Hybrid-Eligible role, you can choose to be designated as:
1) Hybrid: work remotely up to two days per week; or
2) On-Site: work five days per week on-site with ad hoc flexibility.

Note:

The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

$162,800 - $244,200. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements.

• Medical, dental and vision benefits.
• Generous paid time off, including a week‑long company shutdown in the summer and winter.
• Educational assistance programs including student loan repayment.
• Commuting subsidy.
• Matching charitable donations.
• 401(k) retirement plan.
• Other market‑leading benefits.

Vertex is committed to equal employment opportunity and non‑discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at A