Senior Director, Pricing & Market Access

Background and General Summary

Vertex Pharmaceuticals operates at the forefront of scientific innovation and has successfully developed and commercialized multiple breakthrough medicines for Cystic Fibrosis (CF), Casgevy, a gene therapy for sickle cell disease and beta‑thalassemia and Journavx, a novel new treatment for moderate to severe acute pain. Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases including programs in kidney diseases, Type 1 diabetes, among others.

As Vertex grows in scale and complexity, it is establishing a new center of excellence—the Global Pricing & Analytics Group (GPAG)—to build industry‑leading capabilities in global pricing analytics. GPAG will evaluate pricing strategies, measure performance, and deliver actionable insights across regions and the portfolio. Vertex is seeking a Senior Director based in Boston, MA, to lead this new function within the current Global Value & Access Strategy (GVAS) team.

This role reports to the VP of GVAS and will serve on the GVAS Leadership Team.

The Head of GPAG will help shape the group’s long‑term vision and develop a five‑year roadmap for priority technology and pricing capabilities, define the target future state, identify gaps and the resources required to deliver change. The successful candidate will demonstrate strong cross‑functional leadership, thrive in a complex environment, and bring a problem‑solving mindset grounded in strong analytical skills. As a senior member of the GVAS team, this individual must model Vertex’s ethics and culture and be committed to developing the next generation of leaders.

• Lead development of a Global Pricing Analytics capability to sustain value optimization for the Vertex portfolio
  • Assess the current Global pricing data infrastructure and provide recommendations for future requirements
  • Develop a set of Global Pricing Analytics deliverables to guide decision‑making and performance assessments across Vertex disease areas and Regions
  • Build a Global Pricing Analytics reporting infrastructure that integrates multiple data sources and automates insight delivery, including realized prices
• Serve as the Global Value & Access Strategy subject matter expert on Advanced Analytics, including appropriate integration of Artificial Intelligence pilots, capabilities and training for GVAS
• Oversee operations for Global Price Governance including continual updating of guidance documents to audit standards, templates and Regional training
  • Ensure compliance with Global Price Policies in partnership with GVAS Disease Area Leads, and manage the annual review process for Global price floors
  • Develop disease specific performance analytics analyzing negotiation outcomes and achievement of business results relative to pre‑deal analysis
• Lead pricing capability development as required including elements of lifecycle pricing, launch sequencing and risk assessment in close cooperation with relevant stakeholders
• Lead development of systematic P&MA global horizon scanning and internal knowledge management to increase team efficiency and effectiveness of external insights
• Partner with key stakeholders, including US and International Market Access, Global Value & Access Strategy, Global Commercial Strategy, Finance, and DTE to support the development of key GPAG deliverables

• Bachelor’s degree required, ideally in life sciences, post graduate preferred
• 12+ years of direct biotechnology / pharmaceutical industry experience; 5+ years of supervisory / management experience preferred
• Working knowledge of US and/or ex‑US pricing environment is required
• Strong practical, quantitative and analytical skills combined with a sound understanding of how to successfully apply pricing & reimbursement principles to support Vertex
• Excellent working knowledge of US and International Market Access data sets including MMIT, IQVIA, Pricing / GTN (Model‑N), and Real‑World Data (DRG, Market Scan, etc.).
• Experience creating and/or supporting complex analytics and working closely with data scientists
• Strong proficiency in Tableau and/or Power BI, along…