Executive Director, Clinical Business Operations

Are you ready to join a team committed to making a meaningful impact on cancer treatment through the discovery and development of precision medicines? At Kura Oncology, you have an opportunity to be a part of something bigger, with a lasting impact that you can be proud of.

At Kura Oncology, we are working to change the paradigm and improve the science of cancer treatment. As an organization, we strive to cultivate a diverse and talented professional culture driven to develop precision medicine therapeutics.

As we continue to build a leading biotech organization with a strong culture, a patient‑focused mindset and a team focused on relentless execution, we are looking for innovative, passionate professionals to join us and make our vision a reality.

To succeed at Kura, you will need to have a demonstrated ability for excellence in drug discovery and development and a roll‑up‑your‑sleeves attitude. The ideal candidate will possess a values‑driven work style where integrity and grit drive all behaviors, decisions, and actions.

The Executive Director, Clinical Business Operations serves as a strategic leader responsible for driving operational strategy, organizational effectiveness, portfolio governance, and business performance across the Clinical Operations organization. This role acts as a key advisor and thought partner to executive leadership while ensuring the organization possesses the processes, capabilities, insights, and governance necessary to successfully deliver the clinical portfolio.

The Executive Director leads enterprise‑level business operations initiatives spanning Clinical Operations, Clinical Data Sciences, Clinical Systems, Biosample Operations, and other cross‑functional partners. This individual is responsible for establishing scalable operating models, enhancing organizational performance, enabling data‑driven decision making, and driving execution of strategic priorities.

Clinical Operations Leads remain accountable for program strategy and execution while Business Operations provides department‑wide planning, governance, reporting, systems, and business infrastructure.

• Partner with Clinical Operations leadership to develop and execute operational strategy.
• Translate corporate objectives into actionable organizational priorities and execution plans.
• Serve as a strategic advisor to senior leadership on organizational design, resource strategy, capability development, and operational effectiveness.
• Lead transformational initiatives that improve scalability, productivity, and organizational performance.
• Develop and maintain the Clinical Business Operations roadmap, aligning organizational priorities, capabilities, and operational initiatives with the strategic direction of Clinical Operations.

• Establish and oversee governance frameworks supporting clinical operations portfolio execution.
• Lead executive portfolio reviews and performance management processes.
• Develop and deliver executive‑level business insights, performance metrics, and strategic analyses.
• Ensure visibility of portfolio risks, resource constraints, and execution challenges to leadership.

• Define enterprise‑level KPIs and performance measurement frameworks.
• Drive a culture of accountability through transparent performance reporting and operational reviews.
• Lead continuous improvement efforts focused on operational efficiency, quality, and implementation excellence.
• Benchmark organizational performance against industry best practices.
• Standardize planning methodologies, governance processes, reporting, and operational business practices across Clinical Operations to improve consistency and scalability.

• Oversee organizational capacity planning and workforce strategy.
• Partner with Clinical Operations Leads & Finance to support budget development, investment prioritization, and long‑range planning.
• Evaluate organizational capabilities and identify future talent, process, and technology needs.

• Lead highly visible Clinical…