Senior Director of Trade and Channel Management

Senior Director of Trade and Channel Management

Olema Oncology is a clinical-stage biopharmaceutical company committed to transforming the standard of care and improving outcomes for patients living with breast cancer and beyond. It’s an exciting time to be part of Team Olema , with our transfor mation into a fully integrated oncology company well underway , t op-line data from our lead program expected later this year , and our first potential commercial launch on the horizon.

Our lead product candidate,palazestrant, isa novel, orallyavailablecomplete estrogen receptor antagonist (CERAN) and selective estrogen receptor degrader (SERD) currently intwopivotal

Phase 3clinicaltrials.

We expect top-line data from OPERA-01,our ongoing

Phase 3 trial ofpalazestrantas a monotherapy in patients with second- or third-lineER+/HER2-metastatic breast cancer (MBC), in the fallwhich, if successful, could lead to our first potential approval and commercial launchin 2027. OPERA-02,our Phase 3 trial ofpalazestrantin combination withribociblibin patients with frontlineER+/HER2- MBC, is enrolling patients.

Togetherwith its mechanism of action, pharmacokinetic properties,andthe potential todemonstrateactivity in bothESR1wild-type and mutant tumors,palazestranthas the potential to transform the metastatic breast cancer treatment paradigm andaccessa $15 billion global market opportunity.

Our follow-on product candidate, OP-3136, is a potent KAT6 inhibitor withthepotential to generate further value and meaningfullyimpactthemetastatic breastcancertreatment landscape – particularly in combination withpalazestrant.

We recently reported encouraging

Phase 1monotherapydata from this program across multiple solid tumor types andareadvancingpatientenrollment in theongoingcombinationarmsin MBC.

Aspiring to transform the metastatic treatment paradigm is an ambitious endeavor that requires aresolute approach to developing better therapies and apassionateteamdedicated tohelping the patients we serve feel better,longer.

Wepossessadeepcommitment toour shared purpose,the sustained pursuit of excellence, cultivatingthecouragerequiredto advance our programs, drive to succeed, and a collective capacity for adaptability through learning, growth, and evolution. Team Olema is made up of nimble self-starters who bring consistency in their quest for the extraordinary every single day.

Ifyou’rereadyto bepartof atenacious,courageous,agile, andgrowingteam,join us in makinga profound impact,together–
for our patients, for your career, and for what’s beyond .

About the Role>>>

Senior Director of Trade and Channel Management

As the Senior Director of Trade and Channel Management reporting to the Vice President of Market Access, you will be responsible for the strategic design, implementation, and optimization of a high-performing distribution network that ensures patient access while maximizing commercial value.

As a key leader within the U.S. Market Access function, you will oversee the total distribution ecosystem, including Specialty Pharmacy, Distribution and 3PL, while driving the long-term roadmap for trade operations and ensuring the organization is positioned to scale for future therapeutic innovations.

This role is based out of either our Boston or San Francisco office and will require approximately 20% travel.

Your work will primarily encompass:

Strategic Trade & Distribution Architecture

• Define and lead the long-term U.S. distribution strategy and the design of a distribution network to support the launch of our future oncology product(s), including a selection process to select key externals partners (ie. SP, SD, 3PL, etc)
• Provide active account management for specialty pharmacies, wholesalers/distributors, 3PL and other key trade partners to support product availability, service performance, and operational excellence
• Establish, monitor, and manage key performance indicators, service-level expectations, inventory metrics, dispense data, and reporting requirements for channel partners; hold partners accountable while maintaining strong relationships
• Ensure patient accessibility to product through trade partners and specialty pharmacies while supporting compliant…