Senior Manager,Global Commercial Strategy – Early GI,Rheumatology,Neurology Job Boston area,Massachusetts USA,Business

Support development of long-range commercial and portfolio strategy across a subset of Rheumatology, GI, and Neurology disease areas, spanning early pipeline assets, lifecycle opportunities, external innovation, and emerging disease-area opportunities.
Support generation of integrated near-, mid-, and long-term views of disease-area opportunities, risks, and investment priorities to inform portfolio decision-making.
Synthesize scientific, clinical, commercial, access, competitive, and patient insights to identify priority opportunities and strategic trade-offs.
Monitor shifts in the scientific and competitive landscape to identify emerging trends, market discontinuities, and implications for future I&I strategy.
Translate disease-area strategy into clear recommendations, implications, and decision materials for leadership, governance forums, and cross-functional portfolio discussions.
Provide commercial leadership for portfolio prioritization, investment choices, and development opportunities across assigned disease areas.
Pressure-test commercial assumptions, value drivers, risks, uncertainties, and evidence needs that may influence future launch potential, lifecycle value, and portfolio performance.
Lead development of executive-ready materials that communicate strategic rationale, opportunity attractiveness, trade-offs, and recommended actions.
Partner with cross-functional leaders to align on key choices related to indication sequencing, evidence generation, market development, and lifecycle opportunities.
Support disciplined decision-making by ensuring assigned disease-area recommendations are grounded in patient need, scientific opportunity, market potential, access dynamics, and enterprise value.
Lead early commercial assessments for pipeline assets, mechanisms, indications, disease-area opportunities, and potential future product concepts across assigned areas.
Develop and refine product concepts, target product profiles, positioning hypotheses, market archetypes, commercial opportunity assessments, and forecast assumptions.
Ensure unmet need, standard of care, competitive dynamics, patient/HCP insights, and access considerations are translated into differentiated commercial hypotheses.
Provide commercial input to clinical development, evidence generation, lifecycle, and indication sequencing discussions in partnership with cross-functional colleagues.
Build repeatable approaches for high-quality early commercial strategy outputs across the team.
Lead commercial strategy input for external innovation and Business Development opportunities relevant to assigned disease areas.
Guide assessment of strategic fit, market potential, valuation inputs, competitive scenarios, and portfolio implications for potential external opportunities.
Partner with Business Development, R&D, GASP, BAI, and Competitive Intelligence colleagues to pressure-test assumptions and identify key decision points.
Represent the commercial perspective in internal discussions related to external opportunities and broader disease-area strategy as needed.
Influence without direct authority by aligning stakeholders around shared insights, strategic choices, and implications for the I&I portfolio.
Build trusted working relationships across R&D, Medical Affairs, GASP, BAI, Competitive Intelligence, Business Development, and Commercial Regions.
Foster a culture of enterprise thinking, scientific curiosity, accountability, collaboration, and talent development within the team.
Set expectations for responsible, AI-enabled ways of working across the team to improve speed, quality, consistency, and scalability of portfolio strategy outputs.
Champion use of AI-enabled tools to support scientific and competitive landscape synthesis, market insight generation, scenario development, and decision-support efficiency.
Identify opportunities to embed AI into repeatable workflows, templates, portfolio reviews, and strategic decision-support processes.
Use performance insights, stakeholder feedback, and team learnings to continuously improve AI-enabled ways of working across assigned disease areas.

Requirements

Bachelor's degree required; MBA or advanced degree preferred.
6+ years with a BA/BS, 5+ years with MBA/MS, 1+ years with PhD or JD of experience in pharmaceutical, biotechnology, life sciences, commercial development, portfolio strategy, corporate strategy, business development, market research, forecasting, analytics, or related field.
Strong strategic and analytical skills, with ability to synthesize complex scientific, clinical, market, access, and competitive information into clear recommendations.
Experience leading early commercial assessment, business case development, opportunity assessment, or cross-functional strategic planning.
Ability to engage in scientific and clinical dialogue and translate implications for commercial opportunity, differentiation, portfolio value, and enterprise decision-making.
Strong communication, executive presence, problem-solving, and…

Senior Manager, Global Commercial Strategy – Early GI, Rheumatology, Neurology