Senior Manager, Business Insights & Strategy

Tubulis, Inc. is a clinical stage biotech company that generates uniquely matched antibody-drug conjugates (ADCs) with superior biophysical properties that have demonstrated durable on-tumor delivery and long-lasting anti-tumor activity in preclinical models. We recently closed on a Series C fundraising round totaling €344M (US $401M).

The development of novel, effective and safe therapies for the treatment of cancer is one of the main challenges for modern medicine. We want to drive this process forward. The main goal of Tubulis is to become a leading company in the field of targeted therapeutics and ADCs. With a strong team, our own technologies and innovative therapeutic concepts, we are ushering in a new era in the ongoing fight against cancer and share the vision of helping patients world-wide.

Be part of a multidisciplinary and focused team, that works towards getting novel promising ADCs to patients with solid and hematological cancers.

The Senior Manager, Business Insights & Strategy will help build Tubulis’ enterprise strategy and insights capability, turning competitive intelligence, market context, and external signals into decision-ready frameworks and recommendations that shape business development, portfolio, and program strategy. Reporting to the Senior Director of Business Development, this role will function as an internal strategy and analytics partner to Clinical Development, R&D, and Commercial, translating external intelligence into clear implications, options and recommendations.

In this pre-commercial stage, you will build frameworks and capabilities that guide portfolio choices, resource allocation, and business development strategy (e.g., which assets to in-license, how to position programs for out-licensing). This is an opportunity to shape strategic direction at a clinical-stage biotech with direct exposure to executive leadership and Board-level decision-making, while partnering closely with Business Development to inform in-licensing priorities and deal strategy.

This position can be based in Boston, MA or remotely in MA, PA, NY, RI, NJ, NC, MD or FL.

• Evaluate potential oncology assets using data-driven methodologies; apply scalable triage frameworks to screen broad opportunity sets across tumor types, mechanisms and development stages to generate prioritized opportunity lists.
• Conduct holistic asset assessments evaluating strategic fit with Tubulis platforms, operational feasibility, commercial potential, competitive differentiation, and regulatory pathway.
• Build comprehensive business cases for licensing opportunities including market sizing, epidemiology-based patient population forecasts, competitive scenario analysis, revenue projections, and PTRS (probability of technical and regulatory success) calculations in collaboration with Finance and cross-functional stakeholders where appropriate.
• Support active BD execution by preparing partner/meeting briefs, partner mapping, diligence workplans, and decision memos for internal governance (Exec/Board).
• Develop and maintain precedent/deal-comps summaries (terms, structures, and strategic rationale).
• Monitor and assess the oncology ADC competitive landscape across key competing programs, tracking clinical trial progress, regulatory milestones, data readouts, partnerships, and competitive positioning.
• Conduct deep-dive competitive analyses using Clinical Trials.gov, regulatory databases, scientific conferences (ASCO, ESMO, AACR), and company disclosures to identify emerging threats and opportunities and translate them into strategic implications for Tubulis programs.
• Identify emerging trends in ADC technologies (novel payloads, linker…