Accounting Manager

Location: Charlestown, MA

Accounting Manager – Solid Biosciences

Solid Biosciences is a precision genetic medicine company focused on advancing a portfolio of gene therapy candidates targeting rare neuromuscular and cardiac diseases, including Duchenne muscular dystrophy (Duchenne), Friedreich’s ataxia (FA), catecholaminergic polymorphic ventricular tachycardia (CPVT), TNNT2-mediated dilated cardiomyopathy, BAG3-mediated dilated cardiomyopathy, and additional fatal, genetic cardiac diseases. We are advancing a diverse pipeline and delivery platform in the pursuit of uniting experts in science, technology, disease management, and care.

Patient-focused and founded by those directly impacted by Duchenne, Solid’s mission is to improve the daily lives of patients living with devastating rare diseases.

This role will report to the Director, Accounting and will operate in a hybrid work environment, with the expectation of working at Solid’s Corporate Headquarters in Charlestown, MA 2-3 days per week. The Accounting Manager will be a key contributor to the monthly and quarterly close process, balance sheet integrity, internal controls, financial reporting, and process improvement initiatives. The ideal candidate will bring a strong foundation in U.S. GAAP, public company accounting, and Sarbanes-Oxley compliance, along with the ability to operate effectively in a dynamic and fast‑paced biotech environment.

• Prepare and review monthly balance sheet reconciliations for assigned areas, including cash, investments, accounts receivable, prepaids, fixed assets, leases, accrued liabilities, and other key accounts; ensure reconciliations are timely, accurate, and supported by complete audit‑ready documentation.
• Prepare journal entries and supporting schedules for assigned areas of responsibility and ensure transactions are recorded in accordance with U.S. GAAP and Company policies.
• Coordinate assigned close activities to ensure adherence to the monthly and quarterly close calendar.
• Perform monthly and quarterly flux analyses for balance sheet and income statement accounts; investigate root causes of fluctuations and prepare clear, concise, and supportable explanations for management and auditors.
• Support the accounting and operational execution of the Company’s license, collaboration, and other strategic arrangements, including coordination with cross‑functional stakeholders as needed.
• Build strong relationships cross‑functional business partners, including Legal, FP&A, Procurement, Research & Development, and external service providers as needed to support timely, accurate, and decision‑useful financial reporting.
• Support the Company’s SOX 404 compliance efforts through execution and maintenance of internal controls, including process narratives, flowcharts, risk‑control matrices, and related documentation.
• Assist with the preparation, support, and tie‑out of external financial reporting deliverables, including SEC filings such as Forms 10-K, 10-Q, and 8-K, as applicable.
• Support quarterly reviews and annual audits by preparing schedules, responding to auditor requests, and ensuring financial information and documentation are organized, complete, and readily accessible.
• Assist with the evaluation of non‑routine transactions, accounting policy application, and implementation of new accounting guidance, as assigned.
• Serve as a backup resource for key accounting operations, including procure‑to‑pay activities, by developing a strong understanding of end‑to‑end invoice processing, payment controls, and related accounting impacts.
• Identify and drive continuous improvement opportunities across the close process, reconciliations, controls, and systems environment to improve efficiency, scalability, and quality.
• Provide guidance and support to members of the finance organization through close activities, project work, and day‑to‑day collaboration.
• Support special projects and initiatives common to a growing public biotech company, including system implementations, process redesign, business process optimization, and accounting and process readiness activities associated…