Senior) Medical Director- CNS ​/ Neurology

(Senior) Medical Director- CNS / Neurology

When our people share why they joined Rapport and love it here, it comes down to three things: the science, the mission, and the team. At Rapport, we're driven by a passion for developing precision neuromedicines with the potential for fewer side effects, enabling patients and their families to enjoy healthier, more fulfilling lives. And we're doing this with extraordinary science and awesome people (affectionately called Rapptors).

Our innovative scientific platform is centered on Receptor Associate Proteins (RAPs). RAPs are a component of neuronal receptor complexes, which play a crucial role in regulating receptor assembly and function. This precision approach has the potential to revolutionize the development of small molecule therapies. We are excited about the potential of our lead program, RAP-219. Our first indication targets focal epilepsy with additional clinical trials in primary generalized tonic-clonic seizures (PGTCS) and bipolar disorder.

The strength of Rapport comes from our Rapptors – who are united by our mission to improve patients lives. We bring the heart and hustle to advance our science forward, always staying true to our core values. We hope you're as excited about this opportunity as we are!

This Medical Director role offers the opportunity to partner closely with cross-functional leaders to support both clinical development and strategic initiatives in support of the RAP-219 Epilepsy program. The position provides broad exposure to multiple programs, with the chance to work hands-on in the details while growing within a fast-paced, innovative organization.

• Provision of medical input for all clinical deliverables in Rapport's lead program, RAP-219, related to epilepsy
• Driving execution of the assigned clinical program and/or clinical trial in partnership with clinical operations
• Contributing to the development of regulatory documents in support of regulatory submissions, including the clinical sections of INDs and CTAs, safety reports, responses to regulatory authorities and Ethics Committees/IRBs, and other documents as appropriate
• Ensuring that scientific rigor and innovation is at the forefront our Rapport's clinical development strategy and implementation
• Managing engagements with external organizations, key opinion leaders, and advisors
• Supporting medical input into clinical development strategy and protocol reviews
• Working closely with functional partners (Clinical Operations, Data Management, Biostatistics, Regulatory, Medical Affairs) to ensure an integrated and strategic approach to flawless execution and systematic oversight of study protocols
• Establishing strong collaborations with study investigators and outside medical experts and representing Rapport during investigator meetings and advisory boards
• Serving as the medical monitor for assigned studies including design, execution, cleaning, and interpretation of study data

• MD or equivalent medical degree is required
• Minimum of 2 years' experience working in the biotech/pharmaceutical industry in clinical research or drug development
• Strongly preferred advanced knowledge and clinical training and/or drug development experience in Neurology
• Proven clinical development strategist with hands-on experience of designing, implementing, and conducting clinical trials in neurology, Phase 2a – Phase 3
• Working knowledge of epilepsy is required, with proven ability to interpret, discuss and present efficacy and safety data relating to clinical trial(s) and proven ability to understand and interpret basic and clinical scientific research reports
• Demonstrated ability to assimilate clinical data, perform thorough analysis and review, make crisp assessments, and communicate effectively both verbally and in writing
• Demonstrated ability to establish effective scientific partnerships with key stakeholders
• Working knowledge of GCP, clinical trial design, statistics, and regulatory and clinical development processes
• Experience authoring regulatory documents, specifically exposure to the IND/NDA/BLA approval process
• Ability to communicate and work both independently…