Executive Director, Biostatistics

Key Duties and Responsibilities

• Lead and drive scientific statistical methodological expertise to impact the Vertex portfolio through application of best‑in‑class and novel statistical approaches as part of unified development strategies, including oversight of quantitative methods deployed across the portfolio with an eye toward efficiency and innovation.
• Serve as subject‑matter expert and owner, when appropriate, for key biometrics processes and associated operating model(s) related to Biostatistics SOPs, process maps, training and software/tools.
• Own statistical support in the therapeutic areas and/or Global Medical Affairs that the incumbent leads, including early and late clinical developments, post‑marketing studies, real‑world evidence studies and/or analyses supporting reimbursement.
• Drive innovative trial designs in complex or fast‑changing environments to improve trial efficiency and shape the views of the executive team on important matters.
• Serve as a key leader on the Biostatistics Leadership Team to help set and drive vision and execution with respect to data operations, statistics, and statistical reporting and analytics.
• Represent Vertex externally, demonstrating scientific leadership and collaborating in industry, academic and regulatory forums as appropriate.

• Outstanding communication: clarity in writing, excellence in scientific, technical and process writing, influential speech and negotiation, and the ability to explain complex concepts and engage in scientific discourse at the executive level.
• Demonstrated experience developing and leading high‑performing teams.
• Expertise in statistical methodology, including best practices and new industry trends; an agile learner and change agent.
• Executive presence and a high degree of emotional intelligence.

• M.S. or Ph.D. in Statistics or Biostatistics.
• 15 years of relevant work experience, or an equivalent combination of education and experience.

Pay Range: $271,600 - $407,400. The role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay in accordance with federal and state requirements. Compensation is based on skills, competencies, experience, and other factors.

Benefits include medical, dental and vision coverage; generous paid time off, including company shutdowns; educational assistance programs; commuting subsidies; matching charitable donations; 401(k); and other market‑leading benefits.

Vertex is committed to equal employment opportunity and non‑discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E‑Verify employer in the United States and will make reasonable accommodations for qualified individuals with known disabilities.