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Principal Analyst, CGT Agentic Solutions

Job in Boston, Suffolk County, Massachusetts, 02298, USA
Listing for: Vertex Pharmaceuticals, Inc
Full Time position
Listed on 2026-06-03
Job specializations:
  • IT/Tech
    AI Engineer, Data Engineer, Data Analyst, Cloud Computing
Job Description & How to Apply Below
Job Description

General Summary

Vertex is seeking a Principal Analyst, CGT Agentic Solutions to drive the design and implementation of advanced AI-enabled and agentic technologies across our Cell and Gene Therapy (CGT) organization. This role is ideal for a technically strong professional who can bridge data, AI, systems integration, and digital product delivery to create scalable solutions in a complex and highly regulated environment.

The Principal Analyst will work closely with engineering, data, platform, and business analysts to develop intelligent solutions that automate workflows, orchestrate information, enhance decision-making, and improve operational efficiency across CGT. This role will play a key part in shaping how agentic architectures, AI services, and enterprise data ecosystems are applied to real-world scientific and operational challenges.

Key

Duties and Responsibilities:

* Design and support the implementation of agentic and AI-enabled solutions for CGT use cases across commercial, development, manufacturing, quality, and supply chain

* Translate technical and operational needs into solution designs, system requirements, integration patterns, and implementation plans

* Partner with software engineers, data engineers, architects, and product teams to deliver scalable and secure digital solutions

* Define and evaluate agent workflows, orchestration logic, prompt patterns, tool usage, and knowledge retrieval approaches for enterprise applications

* Support development of solutions leveraging large language models, retrieval-augmented generation, workflow automation, APIs, and enterprise data services

* Analyze existing systems, data flows, and technical architectures to identify opportunities for automation, optimization, and modernization

* Contribute to the design of data pipelines, integration frameworks, and system interoperability models supporting agentic platforms

* Ensure solutions align with security, privacy, validation, and compliance requirements in a regulated biotechnology environment

* Establish technical standards, performance measures, and operational monitoring approaches for deployed solutions

* Evaluate emerging AI, cloud, and automation technologies and recommend practical applications within CGT

* Support production readiness, testing strategy, release planning, and continuous improvement of technical solutions

* Serve as a technical leader and subject matter expert for agentic solution capabilities within the CGT digital ecosystem

Knowledge and

Skills:

* Hands-on experience working with AI/ML-enabled applications, enterprise platforms, system integrations, or intelligent automation solutions

* Experience defining and supporting the implementation of technical architectures, APIs, data flows, and workflow automation patterns

* Strong understanding of large language models, agentic systems, orchestration concepts, or applied AI solution design

* Experience collaborating with engineering, architecture, data, and product teams in Agile or product-based delivery environments

* Strong analytical and technical problem-solving skills with the ability to work across complex enterprise ecosystems

* Familiarity with compliance, security, data governance, and validation considerations in regulated environments

Technical

Skills Required:

* Large language model application design and AI solution analysis

* Agentic workflows, orchestration frameworks, and prompt design concepts

* API design/integration and service-based architecture

* Data modeling, data flows, and enterprise integration patterns

* Workflow automation and intelligent process orchestration

* SQL and data analysis skills

* Experience with scripting or programming languages such as Python, SQL, or similar

* Familiarity with cloud platforms and modern data ecosystems

* Understanding of RAG architectures, vector search, knowledge retrieval, and document grounding approaches

* Experience with tools and platforms such as Azure, Databricks, Power BI, Jira, Confluence, Git, or similar technologies

* SDLC, Agile delivery, testing, and release management practices

* Technical documentation, solution design, and systems troubleshooting

Preferred

Skills:

* Advanced degree in a technical or scientific discipline

* Experience in Cell and Gene Therapy, biopharmaceutical manufacturing, quality, or laboratory environments

* Experience with conversational AI, agent frameworks, enterprise copilots, or generative AI platforms

* Familiarity with GxP systems, CSV, validation processes, and regulated platform deployment

* Experience working with cloud-native architectures, data engineering pipelines, or MLOps practices

* Ability to operate as a technical lead across multiple work streams and stakeholders

* Experience evaluating and implementing emerging AI technologies in an enterprise setting

Education and Experience:

* Bachelor's degree in Computer Science, Data Science, Engineering, Bioinformatics, Information Systems, or equivalent

* 5+ years of experience in technical solution…
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