Principal ADS Program Lead

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

This role is in Analytical Data Science, a core function within Product Development Data Sciences (PDD) that provides strategic leadership and scientific rigor across Development  Analytical Data Science teams are mobilized across the portfolio to generate data-driven insights, identify opportunities for scale, and implement impactful solutions.

PDD Analytical Data Science is recognized as a leading hub for top industry talent, operating as an agile workforce to deliver regulatory commitments across the portfolio. We identify, influence, and adopt industry-leading digital and automation solutions, develop analytical approaches to support exploratory analyses, and align statistical programming practices across both early- and late-stage clinical development.

The Analytical Data Science Program Lead serves as a senior leader within the Analytical Data Science function, responsible for guiding both the technical strategy and operational execution across multiple clinical programs or an entire therapeutic area. This role leads a team of highly skilled programmers and junior leaders, ensuring the delivery of high-quality, regulatory-compliant analytical outputs that support key development milestones and health authority submissions.

In addition to overseeing day-to-day delivery, the Analytical Data Science Program Lead is accountable for a broad range of analytical outputs including but not limited to: exploratory analyses, application development and dynamic visualization to enable ongoing data review and scientific insights generation. The Analytical Data Science Program Lead also oversees deliverables originating from cross-functional partners, such as Data Management, ensuring seamless integration into the reporting pipeline.

The Analytical Data Science Program Lead sets priorities, allocates resources, and ensures the scalability and sustainability of programming operations through standardization, automation, and innovation, while providing business context to guide decision‑making with evolving portfolio needs. The Analytical Data Science Program Lead plays a pivotal role in cross‑functional planning and governance, acting as a strategic partner to stakeholders across PDD. As a people leader, the Analytical Data Science Program Lead is accountable for building and developing talent, fostering a culture of technical excellence, and ensuring alignment with both functional and enterprise‑wide data strategies.

• You define and drive the programming and analytical strategy across one or more clinical studies, ensuring alignment with clinical and regulatory objectives, accountable to the TA lead.

• You ensure compliance and inspection readiness by establishing robust quality review processes, maintaining thorough documentation, and proactively addressing potential risks to support internal audits and global health authority inspections.

• You drive and uphold data and programming standards by championing the consistent application of standardized methodologies, tools, and code libraries to ensure efficiency, reproducibility, and alignment with enterprise‑wide data strategy and regulatory expectations.

• You lead cross‑functional planning and execution of data and analytical deliverables, proactively anticipating risks and developing mitigation strategies to ensure quality, consistency, and timeliness.

• You act as a subject matter expert and best practices resource within programming, contributing to the development and refinement of functional standards, tools, and processes.

• You participate in global or complex initiatives, bringing analytical and programming expertise to solve problems spanning studies or functions.

• You contribute to the implementation of innovative approaches, including automation or new delivery models, to enhance efficiency and scalability.

• You collaborate with stakeholders across PDD, such as…